1,870 Result(s)
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Open AccessAre children with IgA nephropathy different from adult patients?
Previously, several studies have indicated that pediatric IgA nephropathy (IgAN) might be different from adult IgAN, and treatment strategies might be also different between pediatric IgAN and adult IgAN.
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Open AccessBenmelstobart, anlotinib and chemotherapy in extensive-stage small-cell lung cancer: a randomized phase 3 trial
Immunochemotherapy is the first-line standard for extensive-stage small-cell lung cancer (ES-SCLC). Combining the regimen with anti-angiogenesis may improve efficacy. ETER701 was a multicenter, double-blind, r...
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Open AccessIdentification, validation and candidate gene analysis of major QTL for Supernumerary spikelets in wheat
The number of spikelets per spike is a key trait that affects the yield of bread wheat (Triticum aestivum L.). Identification of the QTL for spikelets per spike and its genetic effects that could be used in molec...
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Open AccessAggregation promotes charge separation in fullerene-indacenodithiophene dyad
Fast photoinduced charge separation (CS) and long-lived charge-separated state (CSS) in small-molecules facilitate light-energy conversion, while simultaneous attainment of both remains challenging. Here we ac...
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Open AccessCultivation of novel Atribacterota from oil well provides new insight into their diversity, ecology, and evolution in anoxic, carbon-rich environments
The Atribacterota are widely distributed in the subsurface biosphere. Recently, the first Atribacterota isolate was described and the number of Atribacterota genome sequences retrieved from environmental samples ...
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Correction to: Association Between a Failed Prominence Eruption and the Drainage of Mass from Another Prominence
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Open AccessMentoring as a complex adaptive system – a systematic sco** review of prevailing mentoring theories in medical education
Effective mentorship is an important component of medical education with benefits to all stakeholders. In recent years, conceptualization of mentorship has gone beyond the traditional dyadic experienced mentor...
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Mechanical and dam** performances of TPMS lattice metamaterials fabricated by laser powder bed fusion
Lattice metamaterials based on three-period minimum surface (TPMS) are an effective means to achieve lightweight and high-strength materials which are widely used in various fields such as aerospace and ships....
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Open AccessCarbon-based nanomaterials cause toxicity by oxidative stress to the liver and brain in Sprague–Dawley rats
Carbon-based nanomaterials have important research significance in various disciplines, such as composite materials, nanoelectronic devices, biosensors, biological imaging, and drug delivery. Recently, the hum...
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Open AccessPyroptosis-related long-noncoding RNA signature predicting survival and immunotherapy efficacy in patients with lung squamous cell carcinoma
Pyroptosis-related long-noncoding RNAs (PRlncRNAs) play an important role in cancer progression. However, their role in lung squamous cell carcinoma (LUSC) is unclear. A risk model was constructed using the le...
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Open AccessCRISPR-Cas3 and type I restriction-modification team up against blaKPC-IncF plasmid transfer in Klebsiella pneumoniae
We explored whether the Clustered regularly interspaced short palindromic repeat (CRISPR)-Cas and restriction-modification (R-M) systems are compatible and act together to resist plasmid attacks.
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Open AccessAuthor Correction: Vaccination induces broadly neutralizing antibody precursors to HIV gp41
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Open AccessJoint association of weight-adjusted-waist index and physical activity with insulin resistance in adolescents: a cross-sectional study
The weight-adjusted waist index (WWI) is a recently developed obesity metric, and the aim of this study was to investigate the relationship between physical activity (PA) and WWI and the homeostasis model asse...
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Open AccessMelt-electrowriting-enabled anisotropic scaffolds loaded with valve interstitial cells for heart valve tissue Engineering
Tissue engineered heart valves (TEHVs) demonstrates the potential for tissue growth and remodel, offering particular benefit for pediatric patients. A significant challenge in designing functional TEHV lies in...
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Open AccessOptimal antiplatelet therapy after revascularization of left subclavian artery during TEVAR
Thoracic endovascular aortic repair (TEVAR) is a minimally invasive technique used to treat type B aortic dissections. Left subclavian artery (LSA) reconstruction is required when treating patients with involv...
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Open AccessTNIP3 protects against pathological cardiac hypertrophy by stabilizing STAT1
Pathological cardiac hypertrophy is one of the major risk factors of heart failure and other cardiovascular diseases. However, the mechanisms underlying pathological cardiac hypertrophy remain largely unknown....
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Open AccessMacrophage biomimetic nanoparticle-targeted functional extracellular vesicle micro-RNAs revealed via multiomics analysis alleviate sepsis-induced acute lung injury
Patients who suffer from sepsis typically experience acute lung injury (ALI). Extracellular vesicles (EVs) contain miRNAs, which are potentially involved in ALI. However, strategies to screen more effective EV...
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Open AccessLongitudinal metabolomics of human plasma reveal metabolic dynamics and predictive markers of antituberculosis drug-induced liver injury
Tuberculosis (TB) remains the second leading cause of death from a single infectious agent and long-term medication could lead to antituberculosis drug-induced liver injury (ATB-DILI). We established a prospec...
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Publisher Correction: E3 ubiquitin ligase UBR5 modulates circadian rhythm by facilitating the ubiquitination and degradation of the key clock transcription factor BMAL1
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Open AccessEffect of acupuncture on tic disorder: a randomized controlled clinical trial based on energy metabolomics and infrared thermography
Acupuncture is a method for treating tic disorder. However, there is a lack of sufficient clinical objective basis in regards of its treatment efficacy. Indeed, there are structural abnormalities present in en...