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Open AccessAnalysis of clinical features and identification of risk factors in patients with non-alcoholic fatty liver disease based on FibroTouch
Our aim was to explore the correlation between ultrasound attenuation parameter (UAP) and liver stiffness measurement (LSM) based on FibroTouch (China) and clinical features in patients with non-alcoholic fatt...
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Article
Open AccessPalladium catalyzed radical relay for the oxidative cross-coupling of quinolines
Traditional approaches for transition-metal catalyzed oxidative cross-coupling reactions rely on sp2-hybridized starting materials, such as aryl halides, and more specifically, homogeneous catalysts. We report a ...
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Article
Open AccessBreaking scaling relationships in alkynol semi-hydrogenation by manipulating interstitial atoms in Pd with d-electron gain
Pd catalysts are widely used in alkynol semi-hydrogenation. However, due to the existence of scaling relationships of adsorption energies between the key adsorbed species, the increase in conversion is frequen...
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Article
Open AccessHierarchically encapsulating enzymes with multi-shelled metal-organic frameworks for tandem biocatalytic reactions
Biocatalytic transformations in living organisms, such as multi-enzyme catalytic cascades, proceed in different cellular membrane-compartmentalized organelles with high efficiency. Nevertheless, it remains cha...
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Article
Open AccessGold catalysts containing interstitial carbon atoms boost hydrogenation activity
Supported gold nanoparticles are emerging catalysts for heterogeneous catalytic reactions, including selective hydrogenation. The traditionally used supports such as silica do not favor the heterolytic dissoci...
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Article
Open AccessPulmonary MALT Lymphoma has variable features on CT
Pulmonary mucosa-associated lymphoid tissue (MALT) lymphoma is the most common primary pulmonary lymphoma. There are limited studies on imaging features of pulmonary MALT lymphoma. We present the computed tomo...
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Article
Open AccessOptimising surface d charge of AuPd nanoalloy catalysts for enhanced catalytic activity
Understanding the catalytic mechanism of bimetallic nanocatalysts remains challenging. Here, we adopt an adsorbate mediated thermal reduction approach to yield monodispersed AuPd catalysts with continuous chan...
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Article
Open AccessCD8+NKT-like cells regulate the immune response by killing antigen-bearing DCs
CD1d-dependent NKT cells have been extensively studied; however, the function of CD8+NKT-like cells, which are CD1d-independent T cells with NK markers, remains unknown. Here, we report that CD1d-independent CD8+
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Article
Open AccessAssociation of CD8+ T lymphocyte repertoire spreading with the severity of DRESS syndrome
T-cell receptor (TCR)-mediated cross-recognition is a major mechanism in the pathogenesis of drug reaction with eosinophilia and systemic symptoms (DRESS) syndrome. However, the characteristics of the TCR repe...
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Article
Open AccessDax1 and Nanog act in parallel to stabilize mouse embryonic stem cells and induced pluripotency
Nanog expression is heterogeneous and dynamic in embryonic stem cells (ESCs). However, the mechanism for stabilizing pluripotency during the transitions between Nanoghigh and Nanoglow states is not well understoo...
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Article
Open AccessRegulation of T cell proliferation by JMJD6 and PDGF-BB during chronic hepatitis B infection
T cell functional exhaustion during chronic hepatitis B virus (HBV) infection may contribute to the failed viral clearance; however, the underlying molecular mechanisms remain largely unknown. Here we demonstr...
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Article
miR-34/449 miRNAs are required for motile ciliogenesis by repressing cp110
The mir-34/449 family consists of six homologous miRNAs at three genomic loci. Redundancy of miR-34/449 miRNAs and their dominant expression in multiciliated epithelia suggest a functional significance in cilioge...