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Article
Open AccessEffects of different energy levels in low-protein diet on liver lipid metabolism in the late-phase laying hens through the gut-liver axis
The energy/protein imbalance in a low-protein diet induces lipid metabolism disorders in late-phase laying hens. Reducing energy levels in the low-protein diet to adjust the energy-to-protein ratio may improve...
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Article
On Penalized Goal-Reaching Probability Minimization with a Common Shock for an AAI
The authors consider a robust optimal reinsurance and investment problem in a risk model with two dependent classes of insurance business for an Ambiguity-Averse insurer (AAI). The insurer aims to minimize the...
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Article
Comparative Study of High-Temperature Anaerobic Digestion of Municipal Sludge Under Acid/Alkali and Low-Temperature Hydrothermal Synergistic Pretreatment
The efficiency of anaerobic digestion of sludge can be significantly improved through a combination of acid or alkali hydrolysis with low-temperature hydrothermal (LTH) pretreatment. The impact of various agen...
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Article
Open AccessSpatial distribution pattern of immune cells is associated with patient prognosis in colorectal cancer
The spatial context of tumor-infiltrating immune cells (TIICs) is important in predicting colorectal cancer (CRC) patients’ clinical outcomes. However, the prognostic value of the TIIC spatial distribution is ...
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Article
Open AccessThe inverted U-shaped association between blood fibrinogen and rehospitalization risk in patients with heart failure
Fibrinogen, a biomarker of thrombosis and inflammation, is related to a high risk for cardiovascular diseases. However, studies on the prognostic value of blood fibrinogen concentrations for heart failure (HF)...
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Article
Lightweight wildfire smoke monitoring algorithm based on unmanned aerial vehicle vision
Forest fires have a serious impact on people’s living environment. Currently, drones enable rapid detection of forest fires. Due to the limited processing capabilities of onboard drones, the accuracy of smoke ...
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Article
Plasma Ionomic Profile and Interaction Patterns in Coronary Artery Disease Patients
Humans are exposed to various chemical elements that have been associated with the development and progression of diseases such as coronary artery disease (CAD). Unlike previous research, we employed a multi-e...
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Article
Open AccessEmerging roles of ferroptosis in pulmonary fibrosis: current perspectives, opportunities and challenges
Pulmonary fibrosis (PF) is a chronic interstitial lung disorder characterized by abnormal myofibroblast activation, accumulation of extracellular matrix (ECM), and thickening of fibrotic alveolar walls, result...
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Article
Open AccessSingle-nucleus RNA sequencing and lipidomics reveal characteristics of transcriptional and lipid composition in porcine longissimus dorsi muscle
Global per capita meat consumption continues to rise, especially pork. Meat quality is influenced by the content of intramuscular fat (IMF) as a key factor. The longissimus dorsi muscle of Dahe pigs (DHM, IMF: 7....
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Article
A supramolecular fluorescence sensor array for the differentiation of multiple anions and prediction of iodine in artificial urine using machine learning
The simultaneous discrimination and detection of multiple anions in an aqueous solution has been a major challenge due to their structural similarity and low charge radii. In this study, we have constructed a ...
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Article
Open AccessInhibition and transport mechanisms of the ABC transporter hMRP5
Human multidrug resistance protein 5 (hMRP5) effluxes anticancer and antivirus drugs, driving multidrug resistance. To uncover the mechanism of hMRP5, we determine six distinct cryo-EM structures, revealing an...
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Article
Open AccessA cell atlas of the adult female Aedes aegypti midgut revealed by single-cell RNA sequencing
Aedes aegypti is a primary vector for transmitting various arboviruses, including Yellow fever, dengue and Zika virus. The mosquito midgut is the principal organ for blood meal digestion, nutrient absorption and ...
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Article
DSTAN: A Deformable Spatial-temporal Attention Network with Bidirectional Sequence Feature Refinement for Speckle Noise Removal in Thyroid Ultrasound Video
Thyroid ultrasound video provides significant value for thyroid diseases diagnosis, but the ultrasound imaging process is often affected by the speckle noise, resulting in poor quality of the ultrasound video....
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Article
Feasibility test on the analog configuration of electromechanical dimple-tip cantilever for the application of THz metamaterials
We numerically and experimentally developed a cantilever that provided both fast and analog actuation for THz metamaterials (MMs) by properly geometrizing a dimpled tip. Owing to its small size and light mass,...
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Article
Biological variation in the estimated glomerular filtration rate of healthy individuals within 24 h calculated using 2021CKD-EPI equations
Use the MDRD (Modification of Diet in Renal Disease) and 2021 CKD-EPI (Chronic Kidney Disease Epidemiology Collaboration) equation void of race coefficients (CKD-EPICrea, CKD-EPICys-C, and CKD-EPICrea+Cys-C) to e...
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Article
Development and validation of the risk score for estimating suicide attempt in patients with major depressive disorder
Early identification of high-risk patients with Major depressive disorder (MDD) having suicide attempts (SAs) is essential for timely targeted and tailored psychological interventions and medications. This stu...
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Article
Therapeutic effects and mechanisms of isoxanthohumol on DSS-induced colitis: regulating T cell development, restoring gut microbiota, and improving metabolic disorders
Ulcerative colitis (UC) is a severe hazard to human health. Since pathogenesis of UC is still unclear, current therapy for UC treatment is far from optimal. Isoxanthohumol (IXN), a prenylflavonoid from hops an...
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Article
Comparative analysis of preoperative chemoradiotherapy and upfront surgery in the treatment of upper-half rectal cancer: oncological benefits, surgical outcomes, and cost implications
The value of neoadjuvant chemoradiotherapy (CRT) is not absolutely clear for upper-half (> 7–15 cm) rectal cancer. This study aimed to compare the efficacy and safety of radical surgery with preoperative CRT v...
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Article
Fringe enhanced phase unwrap** method based on unscented Kalman filter
Phase unwrap** is a crucial step in almost all Interferometric Synthetic Aperture Radar (InSAR) applications. However, the presence of noise often introduces phase inconsistencies, known as residues, which l...
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Article
Si/TiO2 carbon fiber core encapsulated in hierarchical multiple MXene@Co-MoS2 shells for constructing a free-standing anode of lithium storage
Silicon-based (Si-based) materials offer more possibilities for generating new portable electronic devices due to their high specific capacities. However, their inferior electrical conductivity and volume expa...
