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Article
Open AccessCorrelation of pathological examination with indocyanine green (ICG) intensity gradients: a prospective study in patients with liver tumor
Intraoperative indocyanine green (ICG) fluorescence imaging has been shown to be a new and innovative way to illustrate the optimal resection margin in hepatectomy for hepatocellular carcinoma. This study inve...
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Article
Open AccessDeciphering DED assembly mechanisms in FADD-procaspase-8-cFLIP complexes regulating apoptosis
Fas-associated protein with death domain (FADD), procaspase-8, and cellular FLICE-inhibitory proteins (cFLIP) assemble through death-effector domains (DEDs), directing death receptor signaling towards cell sur...
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Article
Endothelial cell Orai1 is essential for endothelium-dependent contraction of mouse carotid arteries in normotensive and hypertensive mice
Endothelium-dependent contraction (EDC) exists in blood vessels of normotensive animals, but is exaggerated in hypertension. An early signal in EDC is cytosolic Ca2+ rise in endothelial cells. In this study we in...
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Article
Neurophysiological findings in conus medullaris infarction—a case report and systematic review of the literature
Conus medullaris infarction (CMI) is a rare vascular phenomenon that has been scarcely reported in the literature. While previous studies have described the clinical and radiological features of CMI, little at...
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Chapter and Conference Paper
Adaptive Knowledge Sharing in Multi-Task Learning: Insights from Electricity Data Analysis
In time-series machine learning, the challenge of obtaining labeled data has spurred interest in using unlabeled data for model training. Current research primarily focuses on deep multi-task learning, emphasi...
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Article
Open AccessVariations in the crustal structure and strength of plate coupling along the Ryukyu subduction zone
The Ryukyu trench-arc-back arc system is part of the subduction margins of the Philippine Sea plate. Previous studies have indicated that several geophysical and geological characteristics reveal significant v...
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Article
Open AccessThe genome and sex-dependent responses to temperature in the common yellow butterfly, Eurema hecabe
Lepidoptera (butterflies and moths) is one of the most geographically widespread insect orders in the world, and its species play important and diverse ecological and applied roles. Climate change is one of th...
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Article
Open AccessArthroscopic scapholunate ligament repair and dorsal capsulodesis with suture anchor in acute and subacute scapholunate dissociation
The objective of this study was to investigate the potential of arthroscopic scapholunate ligament repair and dorsal capsulodesis with suture anchor as a treatment option for patients experiencing symptomatic ...
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Article
Open AccessCombination of inclusive top-quark pair production cross-section measurements using ATLAS and CMS data at \( \sqrt{s} \) = 7 and 8 TeV
A combination of measurements of the inclusive top-quark pair production cross-section performed by ATLAS and CMS in proton–proton collisions at centre-of-mass energies of 7 and 8 TeV at the LHC is presented. ...
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Article
Open AccessImplicating genes, pleiotropy, and sexual dimorphism at blood lipid loci through multi-ancestry meta-analysis
Genetic variants within nearly 1000 loci are known to contribute to modulation of blood lipid levels. However, the biological pathways underlying these associations are frequently unknown, limiting understandi...
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Article
mRNA (BNT162b2) and Inactivated (CoronaVac) COVID-19 Vaccination and Risk of Adverse Events and Acute Diabetic Complications in Patients with Type 2 Diabetes Mellitus: A Population-Based Study
In Hong Kong, CoronaVac and BNT162b2 have been approved for emergency use owing to the coronavirus disease 2019 (COVID-19) pandemic. Reactions towards the vaccine and the risk of post-vaccination adverse event...
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Article
Open AccessGPR97 triggers inflammatory processes in human neutrophils via a macromolecular complex upstream of PAR2 activation
Neutrophils play essential anti-microbial and inflammatory roles in host defense, however, their activities require tight regulation as dysfunction often leads to detrimental inflammatory and autoimmune diseas...
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Article
Open AccessA saturated map of common genetic variants associated with human height
Common single-nucleotide polymorphisms (SNPs) are predicted to collectively explain 40–50% of phenotypic variation in human height, but identifying the specific variants and associated regions requires huge sa...
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Article
Open AccessEarly-stage COVID-19 pandemic observations on pulmonary embolism using nationwide multi-institutional data harvesting
We introduce a multi-institutional data harvesting (MIDH) method for longitudinal observation of medical imaging utilization and reporting. By tracking both large-scale utilization and clinical imaging results da...
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Article
3D T1-weighted turbo spin echo contrast-enhanced MRI at 1.5 T for frameless brain metastases radiotherapy
Performance of 3D-T1W-TSE has been proven superior to 3D-MP-GRE at 3 T on brain metastases (BM) contrast-enhanced (CE) MRI. However, its performance at 1.5 T is largely unknown and sparsely reported. This stud...
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Article
Open AccessInvolvement of FSP1-CoQ10-NADH and GSH-GPx-4 pathways in retinal pigment epithelium ferroptosis
Retinal pigment epithelium (RPE) degeneration plays an important role in a group of retinal disorders such as retinal degeneration (RD) and age-related macular degeneration (AMD). The mechanism of RPE cell dea...
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Article
Open AccessSarcopenia and its association with objectively measured life-space mobility and moderate-to-vigorous physical activity in the oldest-old amid the COVID-19 pandemic when a physical distancing policy is in force
The oldest-old are highly vulnerable to sarcopenia. Physical distancing remains a common and effective infection-control policy to minimize the risk of COVID-19 transmission during the pandemic. Sarcopenia is ...
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Article
Shape stable poly(vinyl alcohol) hydrogels with immobilized metal hexacyanoferrates for cesium removal from waters
The metal hexacyanoferrates with transition metal ions to replace ferric ions in the face center cubic structure of Prussian blue (PB) crystals are candidate adsorbents for radioactive cesium ions in waters. T...
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Article
Open AccessLRRK2, GBA and their interaction in the regulation of autophagy: implications on therapeutics in Parkinson's disease
Mutations in leucine-rich repeat kinase 2 (LRRK2) and glucocerebrosidase (GBA) represent two most common genetic causes of Parkinson’s disease (PD). Both genes are important in the autophagic-lysosomal pathway (A...
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Article
Effects of a Mindful Parenting Workshop for Parents of Adolescents and Young Adults Following Social Unrest in Hong Kong
The social unrest that began in Hong Kong in 2019 became a threat to public mental health, such as for depression and post-traumatic stress disorders. A supportive family environment is the most effective prot...
