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Article
Open AccessEfficacy of Guselkumab in Treating Nails, Scalp, Hands, and Feet in Patients with Psoriasis and Self-reported Psoriatic Arthritis
The aim of this study was to evaluate guselkumab efficacy on regional psoriasis in a subset of psoriasis patients with a self-reported psoriatic arthritis (PsA) diagnosis.
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Article
Open AccessDNA methylation-free Arabidopsis reveals crucial roles of DNA methylation in regulating gene expression and development
A contribution of DNA methylation to defense against invading nucleic acids and maintenance of genome integrity is uncontested; however, our understanding of the extent of involvement of this epigenetic mark i...
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Article
Maintenance of Response Through up to 4 Years of Continuous Guselkumab Treatment of Psoriasis in the VOYAGE 2 Phase 3 Study
Guselkumab effectively treats moderate-to-severe psoriasis.
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Article
Open AccessImprovement in Patient-Reported Outcomes (Dermatology Life Quality Index and the Psoriasis Symptoms and Signs Diary) with Guselkumab in Moderate-to-Severe Plaque Psoriasis: Results from the Phase III VOYAGE 1 and VOYAGE 2 Studies
Health-related quality of life (HRQoL) may be markedly impaired in patients with moderate-to-severe psoriasis.
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Chapter and Conference Paper
A New Validation Concept for Globally Distributed Multidisciplinary Product Development
Develo** electric vehicles is very important in reducing greenhouse gas (GHG). Since one of the main changes in automotive industry is the entry of new disciplines, the development of electric vehicle as a m...
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Chapter
Isolation, Characterization and Sequence Analysis of Resistance Gene Analogs (RGAs) in Plants Related to Huanglongbing(HLB)
Citrus production is seriously affected by HLB to which no resistant plant is available in the cultivated germplasm. Degenerate primers designed based on conserved NBS (nucleotide binding site) motifs containe...
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Article
Versatile Nitro-Fluorophore as Highly Effective Sensor for Hypoxic Tumor Cells: Design, Imaging and Evaluation
Based on the characteristics of a nitro-group, which can be partially or totally reduced to an amino-group in hypoxic cells, two series of hypoxic sensors containing 7H-Benzimidazole [2,1-a]benz[de]isoquinolin...
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Article
Responses of fractal dimensions ofPicea koraiensis seedlings to different light environments
The changes of fractal dimension ofPicea koraiensis seedlings under different light intensities in natural secondary forests was studied. The results showed that with the change of light environment, crown charac...
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Article
Stress space and strain space formulation of the elasto-plastic constitutive relations for singular yield surface
This paper gives the stress space and the strain space formulations of the elastoplastic constitutive relations at a singular point on a yield surface, discusses the parallelism of the two space formulations a...