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  1. Article

    Open Access

    Cooperation of Rel family members in regulating Aβ1-40-mediated pro-inflammatory cytokine secretion by retinal pigment epithelial cells

    Amyloid-beta (Aβ) is a hallmark component of age-related macular degeneration (AMD), which induces secretion of pro-inflammatory cytokines from retinal pigment epithelium (RPE). Previous studies have shown that p...

    Junran Sun, Peirong Huang, Jian Liang, Jie Li, Mengxi Shen in Cell Death & Disease (2017)

  2. Article

    Open Access

    Photosensitization of A2E triggers telomere dysfunction and accelerates retinal pigment epithelium senescence

    Age-related macular degeneration (AMD) is the leading cause of irreversible vision loss in elderly people. AMD is classified as early, intermediate, advanced non-neovascular, and advanced neovascular forms dep...

    **g Wang, Yiji Feng, Peng Han, Fenghua Wang, Xueting Luo in Cell Death & Disease (2018)