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  1. Article

    Open Access

    Prenatal vitamin intake in first month of pregnancy and DNA methylation in cord blood and placenta in two prospective cohorts

    Prenatal vitamin use is recommended before and during pregnancies for normal fetal development. Prenatal vitamins do not have a standard formulation, but many contain calcium, folic acid, iodine, iron, omega-3...

    John F. Dou, Lauren Y. M. Middleton, Yihui Zhu, Kelly S. Benke in Epigenetics & Chromatin (2022)

  2. Article

    Open Access

    Exosomal annexin A6 induces gemcitabine resistance by inhibiting ubiquitination and degradation of EGFR in triple-negative breast cancer

    Exosomes are carriers of intercellular information that regulate the tumor microenvironment, and they have an essential role in drug resistance through various mechanisms such as transporting RNA molecules and...

    Ting Li, Zhonghua Tao, Yihui Zhu, **aojia Liu, Lei** Wang in Cell Death & Disease (2021)

  3. Article

    Open Access

    Epigenomic signatures in liver and blood of Wilson disease patients include hypermethylation of liver-specific enhancers

    Wilson disease (WD) is an autosomal recessive disease caused by mutations in ATP7B encoding a copper transporter. Consequent copper accumulation results in a variable WD clinical phenotype involving hepatic, neur...

    Charles E. Mordaunt, Dorothy A. Kieffer, Noreene M. Shibata in Epigenetics & Chromatin (2019)