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Article
Open AccessOverexpression of DHX32 contributes to the growth and metastasis of colorectal cancer
Our previous work demonstrates that DHX32 is upregulated in colorectal cancer (CRC) compared to its adjacent normal tissues. However, how overexpressed DHX32 contributes to CRC remains largely unknown. In this...
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Article
ATR/Chk1/Smurf1 pathway determines cell fate after DNA damage by controlling RhoB abundance
ATM- and RAD3-related (ATR)/Chk1 and ataxia–telangiectasia mutated (ATM)/Chk2 signalling pathways play critical roles in the DNA damage response. Here we report that the E3 ubiquitin ligase Smurf1 determines c...