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  1. No Access

    Article

    Identification of novel MEK1 inhibitors by pharmacophore and docking based virtual screening

    Mitogen-activated protein kinase/mitogen-activated protein kinase kinase1 plays a key role in the Ras/Raf/MEK/ERK signaling pathway associated with cell growth, differentiation and development. In an effort to...

    Fangxia Zou, Yifei Yang, Tianfang Ma, Jiayue **… in Medicinal Chemistry Research (2017)

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    Article

    Combined pharmacophore models as virtual screening protocol against BRD4(1) inhibitor

    Bromodomain-containing protein is involved in many essential cellular processes, such as chromosomes for cell cycle progression, cellular viability and embryonic stem cell regulation, which plays a significan...

    Yifei Yang, Fangxia Zou, Leilei Zhao, Yulan Cheng… in Medicinal Chemistry Research (2016)