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Article
Bioactive materials from berberine-treated human bone marrow mesenchymal stem cells promote alveolar bone regeneration by regulating macrophage polarization
Alveolar bone regeneration has been strongly linked to macrophage polarization. M1 macrophages aggravate alveolar bone loss, whereas M2 macrophages reverse this process. Berberine (BBR), a natural alkaloid iso...
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Article
Open AccessThe development of evaluation scale of the patient satisfaction with telemedicine: a systematic review
Since the outbreak of the COVID-19 pandemic, telemedicine become more and more popular, patients attempt to use telemedicine to meet personal medical needs. Patient satisfaction is a key indicator of insight i...
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Article
Integration of transcriptome and metabolome analyses reveals the role of OsSPL10 in rice defense against brown planthopper
OsSPL10 is a negative regulator of rice defense against BPH, knockout of OsSPL10 enhances BPH resistance through upregulation of defense-related genes and accumulation of secondary metabolites.
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Article
Open AccessWhat is nursing professionalism? a concept analysis
Nursing professionalism plays an important role in clinical nursing. However, a clear conceptual understanding of nursing professionalism is lacking.
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Article
Open AccessMorphometric analysis of paired fibula and mandible for optimal fibular mandibular reconstruction in a Chinese population
To analyze the morphology of paired fibula and mandible aiming to choose optimal fibular segments for mandibular reconstruction in a Chinses population. A total of 118 cases of paired mandible and fibula was c...
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Article
A model for the uptake of advance care planning in older cancer adults: a sco** review
Advance care planning (ACP) might assist older cancer patients in expressing their goals, values, and care preferences; yet, the ACP uptake rates in this group are low. The goal of this study is to discover fa...
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Article
O-GlcNAcylation modulates liquid–liquid phase separation of SynGAP/PSD-95
Liquid–liquid phase separation (LLPS) of SynGAP and PSD-95, two abundant proteins that interact in the postsynaptic density (PSD) of neurons, has been implicated in modulating SynGAP PSD enrichment in excitato...
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Article
Open AccessHuman amnion-derived mesenchymal stem cells promote osteogenic differentiation of lipopolysaccharide-induced human bone marrow mesenchymal stem cells via ANRIL/miR-125a/APC axis
Periodontitis is a chronic inflammatory disease inducing the absorption of alveolar bone and leading to tooth loss. Human amnion-derived mesenchymal stem cells (HAMSCs) have been used for studying inflammatory...
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Article
Identification of extracellular vesicles-transported miRNAs in Erlotinib-resistant head and neck squamous cell carcinoma
Erlotinib is an oral tyrosine kinase inhibitor of epidermal growth factor receptor (EGFR) pathway. Although our previous study has proved the efficacy of Erlotinib in head and neck squamous cell carcinoma (HNS...
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Article
Open AccessImmunotherapy with heat shock protein 96 to treat gliomas
Heat shock protein 96 (gp96) is a highly conserved protein in the endoplasmic reticulum. The functions of gp96 include promoting the oncogenesis and progression of glioma. In addition, tumor-derived gp96 can a...
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Article
Open AccessAKT/FOXO1 axis links cross-talking of endothelial cell and pericyte in TIE2-mutated venous malformations
Venous malformations (VMs), most of which associated with activating mutations in the endothelial cells (ECs) tyrosine kinase receptor TIE2, are characterized by dilated and immature veins with scarce smooth m...
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Article
Open AccessIsoform specific FBXW7 mediates NOTCH1 Abruptex mutation C1133Y deregulation in oral squamous cell carcinoma
Our group previously identified that the NOTCH1 Abruptex domain contains the most mutations in Chinese OSCC patients, including a hotspot mutation (C1133Y). FBXW7 is an E3 ubiquitin ligase that regulates a net...
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Article
Assessment of aging characteristics of female condylar trabecular structure by cone-beam computed tomography
This study was performed to analyze the aging-related changes of the female condylar bone mineral density (BMD) and trabecular structure by cone-beam computed tomography (CBCT), and determine whether the condy...
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Article
Open AccessMiR-876-5p modulates head and neck squamous cell carcinoma metastasis and invasion by targeting vimentin
Local or distant metastasis remains the main course of death in head and neck squamous cell carcinoma (HNSCC) patients. MicroRNAs (miRNAs) have been implicated in metastasis of HNSCC, but the mechanisms of the...
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Article
Markov chain analysis of Leading Ones problem
Evolutionary algorithms (EAs) are randomized optimization search techniques, and the theoretical study of the first hitting time is very important in the practical applications of EA. We investigate the first ...
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Article
Asymmetric mutation model in genetic algorithm
Genetic algorithms (GAs) are stochastic optimization techniques, and the theoretical study of the process of GA evolution is very important in the application of GA. Mutation is one of most important operators...
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Article
The angiogenic variation of skeletal site-specific human BMSCs from same alveolar cleft patients: a comparative study
Tissue engineering strategies hold great potential for alveolar cleft reconstruction. Bone marrow stromal cells (BMSCs) from iliac crest and craniofacial regions are candidate seeding cells with site-specific ...
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Article
Effect of acrylonitrile–butadiene–styrene copolymer (ABS) on β-nucleation in β-nucleated polypropylene/ABS blends
β-PP/acrylonitrile–butadiene–styrene (ABS) blends were prepared with PP, ABS and a novel supported β-nucleating agent or β-PP and ABS. The effect of ABS on the β-nucleation of PP and crystallization and meltin...
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Article
Fok1 polymorphism of vitamin D receptor gene contributes to breast cancer susceptibility: a meta-analysis
Several polymorphisms in the vitamin D receptor (VDR) gene have been reported to influence breast cancer risk. However, the published findings have been conflicting. We conducted a meta-analysis of 21 case–contro...
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Article
Measurements of excitation spectra and level lifetimes for highly charged neon ions
Beam foil experiments were carried out for 47 MeV Ne ions passing through C (39 μg/cm2) and A1 (3.4mg/cm2) foils. Highly charged H-, He-., Li-, and Be-like ions were obtained after the foils. The excitation spect...
