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  1. Article

    Author Correction: ADH1C inhibits progression of colorectal cancer through the ADH1C/PHGDH /PSAT1/serine metabolic pathway

    Sha Li, Hong Yang, Wan Li, **-yi Liu, Li-wen Ren in Acta Pharmacologica Sinica (2024)

  2. Article

    Author Correction: Apolipoprotein C1 promotes glioblastoma tumorigenesis by reducing KEAP1/NRF2 and CBS-regulated ferroptosis

    **ang-** Zheng, Wen-lin Chen, Jie Yi, Wan Li, **-yi Liu in Acta Pharmacologica Sinica (2024)

  3. No Access

    Article

    Pharmacologically significant constituents collectively responsible for anti-sepsis action of XueBi**g, a Chinese herb-based intravenous formulation

    Sepsis, a life-threatening health issue, lacks effective medicine targeting the septic response. In China, treatment combining the intravenous herbal medicine XueBi**g with conventional procedures reduces the...

    Chen Cheng, Chao Ren, Mu-zi Li, Yi-hui Liu, Ren-qi Yao in Acta Pharmacologica Sinica (2024)

  4. No Access

    Article

    S670, an amide derivative of 3-O-acetyl-11-keto-β-boswellic acid, induces ferroptosis in human glioblastoma cells by generating ROS and inhibiting STX17-mediated fusion of autophagosome and lysosome

    Glioblastoma (GBM) is the most common malignant tumor in the brain with temozolomide (TMZ) as the only approved chemotherapy agent. GBM is characterized by susceptibility to radiation and chemotherapy resistan...

    Yi-hui Yang, Wan Li, Li-wen Ren, Hong Yang, Yi-zhi Zhang in Acta Pharmacologica Sinica (2024)

  5. Article

    Open Access

    Laser treatment for Cafe-au-lait Macules: a systematic review and meta-analysis

    Nowadays, laser is the mainstay treatment for cafe-au-lait macules (CALMs), but no systematic review has been published to demonstrate the overall efficacy and it’s still controversial which type of laser is o...

    Zi-Zhen Guo, Zhi-Chao Wang, Dun Wang, Ling-Ling Ge in European Journal of Medical Research (2023)

  6. Article

    Open Access

    Vitamin D receptor prevents tumour development by regulating the Wnt/β-catenin signalling pathway in human colorectal cancer

    Colorectal cancer (CRC) is a common disease threatening human lives worldwide, and vitamin D receptor (VDR) contributes protective roles in this disease. However, the molecular mechanisms underlying VDR protec...

    Jie Yu, Qi Sun, Yi Hui, **** Xu, Pancheng Shi, Yu Chen, Yunzhao Chen in BMC Cancer (2023)

  7. Article

    Author Correction: Benzimidazoles induce concurrent apoptosis and pyroptosis of human glioblastoma cells via arresting cell cycle

    Li-wen Ren, Wan Li, **ang-** Zheng, **-yi Liu, Yi-hui Yang in Acta Pharmacologica Sinica (2023)

  8. Article

    Open Access

    Detection of pancreatic cancer with two- and three-dimensional radiomic analysis in a nationwide population-based real-world dataset

    CT is the major detection tool for pancreatic cancer (PC). However, approximately 40% of PCs < 2 cm are missed on CT, underscoring a pressing need for tools to supplement radiologist interpretation.

    Dawei Chang, Po-Ting Chen, Pochuan Wang, Tinghui Wu, Andre Yanchen Yeh in BMC Cancer (2023)

  9. Article

    Author Correction: Apolipoprotein C1 promotes glioblastoma tumorigenesis by reducing KEAP1/NRF2 and CBS-regulated ferroptosis

    **ang-** Zheng, Wen-lin Chen, Jie Yi, Wan Li, **-yi Liu in Acta Pharmacologica Sinica (2022)

  10. No Access

    Article

    Apolipoprotein C1 promotes glioblastoma tumorigenesis by reducing KEAP1/NRF2 and CBS-regulated ferroptosis

    Glioblastoma (GBM), a malignant brain tumor, is a world-wide health problem because of its poor prognosis and high rates of recurrence and mortality. Apolipoprotein C1 (APOC1) is the smallest of apolipoprotein...

    **ang-** Zheng, Wen-lin Chen, Jie Yi, Wan Li, **-yi Liu in Acta Pharmacologica Sinica (2022)

  11. No Access

    Article

    ADH1C inhibits progression of colorectal cancer through the ADH1C/PHGDH /PSAT1/serine metabolic pathway

    Colorectal cancer (CRC) is the third most common cancer in men and the second most common cancer in women worldwide. CRC is the second leading cause of cancer-related deaths. Although some progress in the trea...

    Sha Li, Hong Yang, Wan Li, **-yi Liu, Li-wen Ren in Acta Pharmacologica Sinica (2022)

  12. No Access

    Article

    Benzimidazoles induce concurrent apoptosis and pyroptosis of human glioblastoma cells via arresting cell cycle

    Glioblastoma multiforme (GBM) is the most malignant and lethal primary brain tumor in adults accounting for about 50% of all gliomas. The only treatment available for GBM is the drug temozolomide, which unfort...

    Li-wen Ren, Wan Li, **ang-** Zheng, **-yi Liu, Yi-hui Yang in Acta Pharmacologica Sinica (2022)

  13. No Access

    Article

    Transfer learning for predicting human skin sensitizers

    Computational prioritization of chemicals for potential skin sensitization risks plays essential roles in the risk assessment of environmental chemicals and drug development. Given the huge number of chemicals...

    Chun-Wei Tung, Yi-Hui Lin, Shan-Shan Wang in Archives of Toxicology (2019)

  14. Article

    Open Access

    A positive-feedback loop between tumour infiltrating activated Treg cells and type 2-skewed macrophages is essential for progression of laryngeal squamous cell carcinoma

    Foxp3+ regulatory T (Treg) cells and M2 macrophages are associated with increased tumour progression. However, the interaction between Treg cells and M2 macrophages remains unclear.

    Wei Sun, Fan-Qin Wei, Wei-** Li, Jia-Wei Wei, Hua Zhong in British Journal of Cancer (2017)

  15. Article

    Open Access

    Regular recreational physical activity and risk of head and neck cancer

    Although substantial evidence supports a 20–30% risk reduction of colon cancer, breast cancer, and endometrial cancer by physical activity (PA), the evidence for head and neck cancer (HNC) is limited. Three pu...

    Chen-Lin Lin, Wei-Ting Lee, Chun-Yen Ou, Jenn-Ren Hsiao, Cheng-Chih Huang in BMC Cancer (2017)

  16. No Access

    Article

    Allergy symptoms, serum total immunoglobulin E, and risk of head and neck cancer

    Allergy symptoms have been associated with a reduced head and neck cancer (HNC) risk, while elevated blood immunoglobulin E (IgE) levels have been associated with an increased HNC risk. According to the “proph...

    Hsiao-Chen Liao, Shang-Yin Wu, Chun-Yen Ou, Jenn-Ren Hsiao in Cancer Causes & Control (2016)

  17. Article

    Open Access

    Promoter hypermethylation and silencing of tissue factor pathway inhibitor-2 in oral squamous cell carcinoma

    The treatment of oral squamous cell carcinoma (OSCC) following early detection is associated with good outcomes. Therefore, the survival and prognosis of OSCC patients could be hugely improved by identifying r...

    Yi-Hui Lai, Ru-Yin He, Jian-Liang Chou in Journal of Translational Medicine (2014)

  18. No Access

    Article

    Heritability and genomics of gene expression in peripheral blood

    Fred Wright, Patrick Sullivan and colleagues present the results of a large expression QTL study of peripheral blood using a classic twin design with follow-up replication in independent samples. Their results...

    Fred A Wright, Patrick F Sullivan, Andrew I Brooks, Fei Zou, Wei Sun in Nature Genetics (2014)

  19. No Access

    Article

    Levosimendan versus dobutamine in critically ill patients: a meta-analysis of randomized controlled trials

    To evaluate the clinical efficacy of levosimendan versus dobutamine in critically ill patients requiring inotropic support.

    Xuan Huang, Shu Lei, Mei-fei Zhu in Journal of Zhejiang University SCIENCE B (2013)

  20. No Access

    Article

    Basic aspects of tumor cell fatty acid-regulated signaling and transcription factors

    This article reviews the current knowledge and experimental research about the mechanisms by which fatty acids and their derivatives control specific gene expression involved during carcinogenesis. Changes in ...

    Andrea Comba, Yi-Hui Lin, Aldo Renato Eynard in Cancer and Metastasis Reviews (2011)

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