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    Article

    The impact of blood pressure variability on the development of parenchymal hematoma in acute cerebral infarction with atrial fibrillation

    Although blood pressure variability (BPV) and reperfusion are associated with parenchymal hematoma (PH) after stroke, the relationship between BPV and PH in atrial fibrillation (AF) patients who are at risk of...

    Meng-Ni Wu, Yu-Peng Liu, Yi-On Fong, Yi-Hui Lin, I-Hsiao Yang in Hypertension Research (2024)

  2. Article

    Open Access

    Single-cell transcriptomic analysis reveals a systemic immune dysregulation in COVID-19-associated pediatric encephalopathy

    Unraveling the molecular mechanisms for COVID-19-associated encephalopathy and its immunopathology is crucial for develo** effective treatments. Here, we utilized single-cell transcriptomic analysis and inte...

    Yi Wang, Laurence Don Wai Luu, Shuang Liu in Signal Transduction and Targeted Therapy (2023)

  3. Article

    Open Access

    Macrophage CARD9 mediates cardiac injury following myocardial infarction through regulation of lipocalin 2 expression

    Immune cell infiltration in response to myocyte death regulates extracellular matrix remodeling and scar formation after myocardial infarction (MI). Caspase-recruitment domain family member 9 (CARD9) acts as a...

    Yan Liu, Yi-hui Shao, Jun-meng Zhang, Ying Wang in Signal Transduction and Targeted Therapy (2023)

  4. Article

    Open Access

    Laser treatment for Cafe-au-lait Macules: a systematic review and meta-analysis

    Nowadays, laser is the mainstay treatment for cafe-au-lait macules (CALMs), but no systematic review has been published to demonstrate the overall efficacy and it’s still controversial which type of laser is o...

    Zi-Zhen Guo, Zhi-Chao Wang, Dun Wang, Ling-Ling Ge in European Journal of Medical Research (2023)

  5. Article

    Open Access

    LZTFL1 inhibits kidney tumor cell growth by destabilizing AKT through ZNRF1-mediated ubiquitin proteosome pathway

    LZTFL1 is a tumor suppressor located in chromosomal region 3p21.3 that is deleted frequently and early in various cancer types including the kidney cancer. However, its role in kidney tumorigenesis remains unk...

    Jun Lu, Liang-min Fu, Yun Cao, Yong Fang, Jia-zheng Cao, Yi-hui Pan in Oncogene (2023)

  6. Article

    Open Access

    Positive feedback regulation of lncRNA PVT1 and HIF2α contributes to clear cell renal cell carcinoma tumorigenesis and metastasis

    Long noncoding RNAs (lncRNAs) have been reported to exert important roles in tumors, including clear cell renal cell carcinoma (ccRCC). PVT1 is an important oncogenic lncRNA which has critical effects on onset...

    Ming-xiao Zhang, Li-zhen Zhang, Liang-min Fu, Hao-hua Yao, Lei Tan, Zi-hao Feng in Oncogene (2021)

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    Article

    COL11A1 activates cancer-associated fibroblasts by modulating TGF-β3 through the NF-κB/IGFBP2 axis in ovarian cancer cells

    Ovarian cancer has a unique tumor microenvironment (TME) that enables cancer-associated fibroblasts (CAFs) to interact with cellular and matrix constituents and influence tumor development and migration into t...

    Yi-Hui Wu, Yu-Fang Huang, Tzu-Hao Chang, Chien-Chin Chen, Pei-Ying Wu in Oncogene (2021)

  8. Article

    Open Access

    Predictors of acute cardiovascular events following acute exacerbation period for patients with COPD: a nested case–control study

    It has been noted that there is an increase in the incidence of acute cardiovascular events (CVEs) in patients with chronic obstructive pulmonary disease (COPD) during an acute exacerbation (AE), thereby causi...

    Wei-** Hu, Tsokyi Lhamo, Feng-ying Zhang, **g-qing Hang in BMC Cardiovascular Disorders (2020)