11 Result(s)
within
Yi Zeng Liang
Proteomics
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Article
Resolution and identification of the acidic fraction of a petroleum ether extract ofRadix Rehmanniae Preparata by an evolving chemometric approach
An evolving approach is described for analyzing the acidic components of a petroleum ether extract of Radix Rehmanniae Preparata. The latter was extracted, separated and derivatized. The subsequent separation ...
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Article
Simultaneous Determination of Enalapril and Enalaprilat in Human Plasma by LC-MS: Application to a Bioequivalence Study
A rapid, simple and specific liquid chromatography-electrospray ionization mass spectrometry (LC-ESI-MS) method has been developed and validated for the simultaneous determination of enalapril and its major ac...
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Article
Development and Validation of LC–MS Method for the Determination of Hydroxyzine Hydrochloride in Human Plasma and Subsequent Application in a Bioequivalence Study
A rapid, simple and specific liquid chromatography-electrospray ionization mass spectrometry method has been developed and validated for the determination of hydroxyzine hydrochloride in human plasma. Samples ...
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Article
UPLC–MS–MS Analysis of Baicalin in the Cerebrospinal Fluid of Rabbits: Application to a Pharmacokinetic Study
A sensitive and selective ultra-performance liquid chromatographic–tandem mass spectrometric method has been developed for analysis of baicalin in the cerebrospinal fluid of rabbits. Samples were separated on a C
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Article
Essential Oil Composition of Osmanthus fragrans Varieties by GC-MS and Heuristic Evolving Latent Projections
The essential oils from two varieties of Osmanthus fragrans have been extracted by steam distillation and analyzed by gas chromatography-mass spectrometry with the help of heuristic evolving latent projections (H...
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Article
Comments on the Baseline Removal Method Based on Quantile Regression and Comparison of Several Methods
Several months ago, a paper by Komsta describing a method of baseline removal based on quantile regression for chromatographic datasets was published in this journal entitled “Comparison of Several Methods of ...
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Article
Investigation of Scrambled Ions in Tandem Mass Spectra. Part 1. Statistical Characterization
Scrambled ions have become the focus of recent investigations of peptide fragmentation. Here, an investigation of more than 390,000 high quality CID mass spectra is presented to explore the extent of scrambled...
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Article
QSRR Study on Flavor Compounds of Diverse Structures on Different Columns with the Help of New Chemometric Methods
A quantitative structure–retention relationship study was performed for 286 flavor compounds with highly structural diversity on different stationary phases of different polarities. Firstly, the structure–rete...
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Article
Investigation of Scrambled Ions in Tandem Mass Spectra, Part 2. On the Influence of the Ions on Peptide Identification
A comprehensive investigation was performed to understand the influence of sequence scrambling in peptide ions on peptide identification results. To achieve this, four tandem mass spectrometry datasets with sc...
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Article
Comparisons of Five Algorithms for Chromatogram Alignment
In this study, five frequently used war** algorithms [correlation optimized war** (COW), recursive alignment by fast Fourier transform (RAFFT), dynamic time war**, variable penalty dynamic war**, and p...
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Article
Retention Indices for Identification of Aroma Compounds by GC: Development and Application of a Retention Index Database
In this paper we focus on the development and application of a retention index database for aroma compounds with high structural diversity. Retention indices of over 300 aroma compounds were determined on thre...
