-
Article
Resolution and identification of the acidic fraction of a petroleum ether extract ofRadix Rehmanniae Preparata by an evolving chemometric approach
An evolving approach is described for analyzing the acidic components of a petroleum ether extract of Radix Rehmanniae Preparata. The latter was extracted, separated and derivatized. The subsequent separation ...
-
Article
Simultaneous Determination of Enalapril and Enalaprilat in Human Plasma by LC-MS: Application to a Bioequivalence Study
A rapid, simple and specific liquid chromatography-electrospray ionization mass spectrometry (LC-ESI-MS) method has been developed and validated for the simultaneous determination of enalapril and its major ac...
-
Article
Development and Validation of LC–MS Method for the Determination of Hydroxyzine Hydrochloride in Human Plasma and Subsequent Application in a Bioequivalence Study
A rapid, simple and specific liquid chromatography-electrospray ionization mass spectrometry method has been developed and validated for the determination of hydroxyzine hydrochloride in human plasma. Samples ...
-
Article
UPLC–MS–MS Analysis of Baicalin in the Cerebrospinal Fluid of Rabbits: Application to a Pharmacokinetic Study
A sensitive and selective ultra-performance liquid chromatographic–tandem mass spectrometric method has been developed for analysis of baicalin in the cerebrospinal fluid of rabbits. Samples were separated on a C
-
Article
Essential Oil Composition of Osmanthus fragrans Varieties by GC-MS and Heuristic Evolving Latent Projections
The essential oils from two varieties of Osmanthus fragrans have been extracted by steam distillation and analyzed by gas chromatography-mass spectrometry with the help of heuristic evolving latent projections (H...
-
Article
Comments on the Baseline Removal Method Based on Quantile Regression and Comparison of Several Methods
Several months ago, a paper by Komsta describing a method of baseline removal based on quantile regression for chromatographic datasets was published in this journal entitled “Comparison of Several Methods of ...
-
Article
QSRR Study on Flavor Compounds of Diverse Structures on Different Columns with the Help of New Chemometric Methods
A quantitative structure–retention relationship study was performed for 286 flavor compounds with highly structural diversity on different stationary phases of different polarities. Firstly, the structure–rete...
-
Article
Comparisons of Five Algorithms for Chromatogram Alignment
In this study, five frequently used war** algorithms [correlation optimized war** (COW), recursive alignment by fast Fourier transform (RAFFT), dynamic time war**, variable penalty dynamic war**, and p...
-
Article
Retention Indices for Identification of Aroma Compounds by GC: Development and Application of a Retention Index Database
In this paper we focus on the development and application of a retention index database for aroma compounds with high structural diversity. Retention indices of over 300 aroma compounds were determined on thre...