865 Result(s)

Article

Methylprednisolone Modulates the Tfr/Tfh ratio in EAE-Induced Neuroinflammation through the PI3K/AKT/FoxO1 and PI3K/AKT/mTOR Signalling Pathways

Methylprednisolone (MP) is a potent glucocorticoid that can effectively inhibit immune system inflammation and brain tissue damage in Multiple sclerosis (MS) patients. T follicular helper (Tfh) cells are a sub...

Nan Wu, Yun Zhao, Minjun **ao, Hui Liu, Hongliang Chen, Bin Liu… in Inflammation (2024)

Article

Incidence of metabolic syndrome in patients with unilateral or bilateral staghorn renal stones and its impact on percutaneous nephrolithotomy outcomes

To evaluate the incidence of metabolic syndrome (MetS) in patients with unilateral and bilateral staghorn calculi (SC) and evaluate the impact on the outcome of percutaneous nephrolithotomy (PCNL).

Zhonghua Shen, Linguo **e, Di Luo, Haijie **e, Hongyang Chen, Chunyu Liu in BMC Urology (2024)

Article

The impact of intraoperative hypotension on postoperative acute kidney injury, mortality and length of stay following off-pump coronary artery bypass grafting surgery: a single-center retrospective cohort study

Off-pump coronary artery bypass grafting (OPCABG) presents distinct hemodynamic characteristics, yet the relationship between intraoperative hypotension and short-term adverse outcomes remains clear. Our study...

Cheng **ao, Ming Yang, Lei Cao, Fang Chen, Sheng **g, Yuting Tan… in BMC Anesthesiology (2024)

Article

CROCuS, a Phase II Study Evaluating the Antiviral Activity, Clinical Outcomes, and Safety of Rilematovir in Children Aged ≥ 28 Days and ≤ 3 Years with Acute Respiratory Tract Infection Due to Respiratory Syncytial Virus

Respiratory syncytial virus (RSV) causes significant morbidity and mortality in children aged ≤ 5 years and adults aged ≥ 60 years worldwide. Despite this, RSV-specific therapeutic options are limited. Rilemat...

Fernando Ferrero, Chien-Yu Lin, Johannes Liese, Kleber Luz… in Pediatric Drugs (2024)

Article

Retraction Note: Circular RNA circStag1 promotes bone regeneration by interacting with HuR

Gaoyang Chen, Canling Long, Shang Wang, Zhenmin Wang, **n Chen, Wanze Tang… in Bone Research (2024)

Article

Learning and depicting lobe-based radiomics feature for COPD Severity staging in low-dose CT images

Chronic obstructive pulmonary disease (COPD) is a prevalent and debilitating respiratory condition that imposes a significant healthcare burden worldwide. Accurate staging of COPD severity is crucial for patie...

Meng Zhao, Yanan Wu, Yifu Li, **aoyu Zhang, Shuyue **a… in BMC Pulmonary Medicine (2024)

Article

Optimized RNA interference therapeutics combined with interleukin-2 mRNA for treating hepatitis B virus infection

This study aimed to develop a pan-genotypic and multifunctional small interfering RNA (siRNA) against hepatitis B virus (HBV) with an efficient delivery system for treating chronic hepatitis B (CHB), and explo...

Wen**g Zai, Min Yang, Kuan Jiang, Juan Guan… in Signal Transduction and Targeted Therapy (2024)

Article

Correction: Overexpressed KCNK1 regulates potassium channels affecting molecular mechanisms and biological pathways in bladder cancer

Wei Zhang, **ao‑Song Chen, Ying Wei, **ao‑Min Wang… in European Journal of Medical Research (2024)

Article

Radiomics analysis based on CT for predicting lymph node metastasis and prognosis in duodenal papillary carcinoma

Radiomics has been demonstrated to be strongly associated with TNM stage and patient prognosis. We aimed to develop a model for predicting lymph node metastasis (LNM) and survival.

Chao-Tao Tang, Yonghui Wu, Longzhou Jiang, Chun-Yan Zeng… in Insights into Imaging (2024)

Article

Autophagy-related molecular clusters identified as indicators for distinguishing active and latent TB infection in pediatric patients

Autophagy is crucial for controlling the manifestation of tuberculosis. This study intends to discover autophagy-related molecular clusters as biomarkers for discriminating between latent tuberculosis (LTBI) a...

Yang Yu, Jie Hua, Liang Chen in BMC Pediatrics (2024)

Article

Minimally invasive stabilization using screws and cement for acetabular metastatic tumor: a case report

The aim of this case report is to evaluate minimally invasive stabilization using screws and cement for acetabular metastatic tumor and summarize the indications and contraindications for minimally invasive st...

Yang Chen, Yunus Akbar, Haibin **ang… in Journal of Medical Case Reports (2024)

Article

Tumor-resident microbiota contributes to colorectal cancer liver metastasis by lactylation and immune modulation

The role of tumor-resident microbiota in modulating tumor immunity remains unclear. Here, we discovered an abundance of intra-tumoral bacteria, such us E.coli, residing and resulting in Colorectal cancer liver me...

Jian Gu, **aozhang Xu, **angyu Li, Lei Yue, **aowen Zhu, Qiuyang Chen, Ji Gao… in Oncogene (2024)

Article

Risk of carpal tunnel syndrome among patients with osteoarthritis: a US population-based study

Carpal tunnel syndrome (CTS), an entrapment neuropathy caused by pressure of the median nerve, is a progressive condition that can lead to a decreased quality of life. Studies suggest an association between CT...

Shuang Chen, Tina Ho, Julius Asubonteng, Rachel E. Sobel… in BMC Musculoskeletal Disorders (2024)

Article

Chlamydia psittaci detected at a live poultry wholesale market in central China

We investigated the presence of Chlamydia psittaci in poultry and the environment in live poultry wholesale markets in Changsha during 2021–2022 and conducted a phylogenetic analysis to understand its distributio...

Rusheng Zhang, Huiyuan Fu, Can Luo, Zheng Huang, Ruiqing Pei… in BMC Infectious Diseases (2024)

Article

Association between estimated glucose disposal rate and atrial fibrillation recurrence in patients undergoing radiofrequency catheter ablation: a retrospective study

Previous studies have shown a clear link between insulin resistance (IR) and an elevated risk of atrial fibrillation (AF). However, the relationship between the estimated glucose disposal rate (eGDR), which se...

**aozhong Li, Zheng Zhou, Zhen **a, Youzheng Dong… in European Journal of Medical Research (2024)

Article

Plasma 25-hydroxyvitamin D deficiency in the peri-operative period is associated with survival outcome in colorectal cancer patients: a meta-analysis

Surgery had a significant impact on 25-hydroxyvitamin D (25-(OH)D) levels. Uncertainty still existed regarding the effects of peri-operative 25(OH)D deficiency on colorectal cancer (CRC) patients’ prognosis. T...

Baojia Zheng, Jianchang Chen, **aohua Gong in BMC Surgery (2024)

Article

The potential of organoids in renal cell carcinoma research

Renal cell carcinoma, a leading cause of death in urological malignancies, arises from the nephron. Its characteristics include diversity in disease biology, varied clinical behaviors, different prognoses, and...

Qiuyang Chen, Xuan Sun, Yubei Li, **nyue Yang, Xuejian Yang, Haifei Xu… in BMC Urology (2024)

Article

Analysis of correlation between BMI and TWL% outcome following metabolic and bariatric surgery: a retrospective study using restricted cubic spline

This study aimed to examine the correlation between preoperative body mass index (BMI) and adequate percentage of total weight loss (TWL%) outcome and present evidence of tiered treatment for patients with obe...

Guanyang Chen, Zhehong Li, Liang Wang, Qiqige Wuyun, Qing Sang, **g Wang… in BMC Surgery (2024)

Article

A comparison of hemodynamic measurement methods during orthotopic liver transplantation: evaluating agreement and trending ability of PiCCO versus pulmonary artery catheter techniques

Significant hemodynamic changes occur during liver transplantation, emphasizing the importance of precious and continuous monitoring of cardiac output, cardiac index, and other parameters. Although the monitor...

Yulu Feng, Zexi Ye, Yuekun Shen, Wei **ong, **aoxiang Chen… in BMC Anesthesiology (2024)

Article

Impact of Online Video Game-Based Dichoptic Training on Binocular Vision Rehabilitation in Post-surgical Patients with Intermittent Exotropia

Dichoptic training has emerged as a promising rehabilitation approach for improving binocular visual function in patients with strabismus. A prospective observational study design was employed to assess the ef...

Xuan Qiu, Yusong Zhou, ** Yu, Zhonghao Wang, Tao Shen… in Ophthalmology and Therapy (2024)