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Article
Open AccessGut butyrate-producers confer post-infarction cardiac protection
The gut microbiome and its metabolites are increasingly implicated in several cardiovascular diseases, but their role in human myocardial infarction (MI) injury responses have yet to be established. To address...
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Article
Open AccessTumor endothelial marker 1 is upregulated in heart after cardiac injury and participates in cardiac remodeling
Tumor endothelial marker 1 (TEM1) is a transmembrane glycoprotein that appears on mesenchymal lineage-derived cells during embryogenesis, but its expression greatly reduces after birth. Re-upregulation of TEM1...
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Article
Open AccessSubtle cardiac dysfunction in lymphoma patients receiving low to moderate dose chemotherapy
Left ventricular (LV) global peak systolic longitudinal strain (GLS) is a sensitive measurement for detecting subtle LV systolic dysfunction and a powerful prognostic predictor. However, the clinical implicati...
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Article
Human embryonic-stem-cell-derived cardiomyocytes regenerate non-human primate hearts
Regeneration of the heart muscle after myocardial infarction with cardiomyocytes derived from human embryonic stem cells is demonstrated in non-human primates, with the grafts showing evidence of electromechan...