4 Result(s)
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Yasutsugu Suzuki
Science, Humanities and Social Sciences, multidisciplinary
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Article
Open AccessDefective viral genomes as therapeutic interfering particles against flavivirus infection in mammalian and mosquito hosts
Arthropod-borne viruses pose a major threat to global public health. Thus, innovative strategies for their control and prevention are urgently needed. Here, we exploit the natural capacity of viruses to genera...
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Article
Open AccessTargeted delivery of CRISPR-Cas9 ribonucleoprotein into arthropod ovaries for heritable germline gene editing
Cas9-mediated gene editing is a powerful tool for addressing research questions in arthropods. Current approaches rely upon delivering Cas9 ribonucleoprotein (RNP) complex by embryonic microinjection, which is...
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Article
Open AccessIn vitro and in vivo host range of Anopheles gambiae densovirus (AgDNV)
AgDNV is a powerful gene transduction tool and potential biological control agent for Anopheles mosquitoes. Using a GFP reporter virus system, we investigated AgDNV host range specificity in four arthropod cell l...
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Article
Open AccessA viral over-expression system for the major malaria mosquito Anopheles gambiae
Understanding pathogen/mosquito interactions is essential for develo** novel strategies to control mosquito-borne diseases. Technical advances in reverse-genetics, such as RNA interference (RNAi), have facil...
