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  1. No Access

    Article

    Value of Highly Sensitive Fucosylated Fraction of Alpha-Fetoprotein for Prediction of Hepatocellular Carcinoma Recurrence After Curative Treatment

    The fucosylated fraction of alpha-fetoprotein (AFP-L3) has been used as a diagnostic marker for hepatocellular carcinoma (HCC). Recently, a highly sensitive immunoassay using an on-chip electrokinetic reaction...

    Yasushi Tamura, Takeshi Suda, Shigeki Arii, Michio Sata… in Digestive Diseases and Sciences (2013)

  2. No Access

    Article

    Clinical Advantage of Highly Sensitive On-Chip Immunoassay for Fucosylated Fraction of Alpha-Fetoprotein in Patients with Hepatocellular Carcinoma

    Alpha-fetoprotein (AFP) has been widely used as a diagnostic master for hepatocellular carcinoma (HCC), and the fucosylated fraction of AFP (AFP-L3) has been reported to be a specific marker for HCC. However, ...

    Yasushi Tamura, Masato Igarashi, Hirokazu Kawai… in Digestive Diseases and Sciences (2010)

  3. No Access

    Article

    Fucosylated Fraction of Alpha-Fetoprotein as a Predictor of Prognosis in Patients with Hepatocellular Carcinoma After Curative Treatment

    The aim of this study was to evaluate the clinical usefulness of measuring the Lens culinaris agglutinin-reactive fraction of alpha-fetoprotein (AFP-L3) for prognostic predictor in patients with hepatocellular ca...

    Yasushi Tamura, Masato Igarashi, Takeshi Suda… in Digestive Diseases and Sciences (2010)

  4. No Access

    Article

    Serum Alpha-Fetoprotein Levels During and After Interferon Therapy and the Development of Hepatocellular Carcinoma in Patients with Chronic Hepatitis C

    The association between serum alpha-fetoprotein (AFP) levels during and after interferon (IFN) therapy and the development of hepatocellular carcinoma (HCC) was evaluated in patients with chronic hepatitis C (...

    Yasushi Tamura, Satoshi Yamagiwa, Yohei Aoki, So Kurita… in Digestive Diseases and Sciences (2009)

  5. No Access

    Article

    Predisposition to mouse thymic lymphomas in response to ionizing radiation depends on variant alleles encoding metal-responsive transcription factor-1 (Mtf-1)

    Genetic predisposition to cancers is significant to public health because a high proportion of cancers probably arise in a susceptible human subpopulation. Using a mouse model of γ-ray-induced thymic lymphomas, w...

    Yasushi Tamura, Masaki Maruyama, Yukio Mishima, Hiromi Fujisawa, Miki Obata… in Oncogene (2005)

  6. No Access

    Article

    Map** of genetic modifiers of thymic lymphoma development in p53-knockout mice

    The strain dependency of the spectrum and latency of tumors has been reported in p53-deficient (KO) mice, suggesting the presence of modifiers for the outcome of the p53 deficiency. The modifiers provide clues to...

    Yukie Ochiai, Yasushi Tamura, Yuko Saito, Atsushi Matsuki, Yu-ichi Wakabayashi… in Oncogene (2003)

  7. No Access

    Article

    Genetic loci controlling susceptibility to γ-ray-induced thymic lymphoma

    BALB/c is a susceptible strain for the development of γ-ray induced mouse thymic lymphoma whereas MSM shows resistance. Association analysis of 220 backcross mice between the two strains using 67 markers was c...

    Yuko Saito, Yukie Ochiai, Yasumitsu Kodama, Yasushi Tamura, Tadayuki Togashi… in Oncogene (2001)

  8. No Access

    Chapter

    Mechanism of Anti-Proliferative Action of Eicosapentaenoic Acid (EPA) in Vascular Cell Growth: Its Effect on Signal Transduction System

    In late 1970s, Dyerberg and Bang reported that a low incidence of cardiovascular thrombotic disorders could be ascribed to a large intake of marine diet rich in ω-3 polyunsaturated fatty acids (PUFA)1. Since then...

    Takashi Terano, Aizan Hirai, Tatsuya Shiina… in Eicosanoids and other Bioactive Lipids in … (1997)