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    Article

    Organelle membrane-specific chemical labeling and dynamic imaging in living cells

    Lipids play crucial roles as structural elements, signaling molecules and material transporters in cells. However, the functions and dynamics of lipids within cells remain unclear because of a lack of methods ...

    Tomonori Tamura, Alma Fujisawa, Masaki Tsuchiya, Yuying Shen in Nature Chemical Biology (2020)

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    Chapter

    Role of Intra- and Inter-mitochondrial Membrane Contact Sites in Yeast Phospholipid Biogenesis

    Eukaryotic cells exhibit intracellular compartments called organelles wherein various specialized enzymatic reactions occur. Despite the specificity of the characteristic functions of organelles, recent studie...

    Yasushi Tamura, Toshiya Endo in Organelle Contact Sites (2017)

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    Article

    Biosynthesis and roles of phospholipids in mitochondrial fusion, division and mitophagy

    Mitochondria move, fuse and divide in cells. The dynamic behavior of mitochondria is central to the control of their structure and function. Three conserved mitochondrial dynamin-related GTPases (i.e., mitofu...

    Qiang Zhang, Yasushi Tamura, Madhuparna Roy in Cellular and Molecular Life Sciences (2014)

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    Article

    Value of Highly Sensitive Fucosylated Fraction of Alpha-Fetoprotein for Prediction of Hepatocellular Carcinoma Recurrence After Curative Treatment

    The fucosylated fraction of alpha-fetoprotein (AFP-L3) has been used as a diagnostic marker for hepatocellular carcinoma (HCC). Recently, a highly sensitive immunoassay using an on-chip electrokinetic reaction...

    Yasushi Tamura, Takeshi Suda, Shigeki Arii, Michio Sata in Digestive Diseases and Sciences (2013)

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    Article

    Clinical Advantage of Highly Sensitive On-Chip Immunoassay for Fucosylated Fraction of Alpha-Fetoprotein in Patients with Hepatocellular Carcinoma

    Alpha-fetoprotein (AFP) has been widely used as a diagnostic master for hepatocellular carcinoma (HCC), and the fucosylated fraction of AFP (AFP-L3) has been reported to be a specific marker for HCC. However, ...

    Yasushi Tamura, Masato Igarashi, Hirokazu Kawai in Digestive Diseases and Sciences (2010)

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    Article

    Fucosylated Fraction of Alpha-Fetoprotein as a Predictor of Prognosis in Patients with Hepatocellular Carcinoma After Curative Treatment

    The aim of this study was to evaluate the clinical usefulness of measuring the Lens culinaris agglutinin-reactive fraction of alpha-fetoprotein (AFP-L3) for prognostic predictor in patients with hepatocellular ca...

    Yasushi Tamura, Masato Igarashi, Takeshi Suda in Digestive Diseases and Sciences (2010)

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    Article

    Serum Alpha-Fetoprotein Levels During and After Interferon Therapy and the Development of Hepatocellular Carcinoma in Patients with Chronic Hepatitis C

    The association between serum alpha-fetoprotein (AFP) levels during and after interferon (IFN) therapy and the development of hepatocellular carcinoma (HCC) was evaluated in patients with chronic hepatitis C (...

    Yasushi Tamura, Satoshi Yamagiwa, Yohei Aoki, So Kurita in Digestive Diseases and Sciences (2009)