Skip to main content

5 Result(s)

within Yannick Le Meur Remove this filter Pharmacology/Toxicology Remove this filter

and

  1. Article

    Open Access

    Pharmacokinetics of Prolonged-Release Once-Daily Formulations of Tacrolimus in De Novo Kidney Transplant Recipients: A Randomized, Parallel-Group, Open-Label, Multicenter Study

    Different prolonged-release formulations of tacrolimus are available. To date, the pharmacokinetic (PK) profile of LCP-tacrolimus (LCPT; Envarsus®) has not been compared with PR-Tac (Advagraf®) in de novo kidney ...

    Nassim Kamar, Elisabeth Cassuto, Giovanni Piotti, Mirco Govoni… in Advances in Therapy (2019)

    Download PDF (1197 KB) View Article

  2. No Access

    Article

    Tacrolimus Population Pharmacokinetic-Pharmacogenetic Analysis and Bayesian Estimation in Renal Transplant Recipients

    Objectives: The aims of this study were (i) to investigate the population pharmacokinetics of tacrolimus in renal transplant recipients, including the influence of biological and pharmacogenetic ...

    Khaled Benkali, Aurelie Prémaud, Nicolas Picard… in Clinical Pharmacokinetics (2009)

  3. No Access

    Article

    A Double Absorption-Phase Model Adequately Describes Mycophenolic Acid Plasma Profiles in De Novo Renal Transplant Recipients Given Oral Mycophenolate Mofetil

    Mycophenolic acid (MPA) shows complex plasma concentrationtime profiles, particularly in the immediate (first month) post-transplantation phase for which no relevant pharmacokinetic model has been proposed thu...

    Aurélie Prémaud, Jean Debord, Annick Rousseau, Yannick Le Meur… in Clinical Pharmacokinetics (2005)

  4. No Access

    Article

    Simultaneous estimation of cyclosporin and mycophenolic acid areas under the curve in stable renal transplant patients using a limited sampling strategy

    Objectives: Area under the curve (AUC)-based monitoring of cyclosporin (CsA) could help to optimise therapeutic drug monitoring in certain transplant patients in addition to trough concentration ...

    Chantal Le Guellec, Matthias Büchler… in European Journal of Clinical Pharmacology (2002)

  5. No Access

    Article

    Application of a Gamma Model of Absorption to Oral Cyclosporin

    Background: Some drugs, such as cyclosporin, exhibit flat and delayed absorption profiles, with a correlation between the delay and the peak width. Such profiles can be described by an absorption...

    Dr Jean Debord, Eléonore Risco, Michel Harel, Yannick Le Meur… in Clinical Pharmacokinetics (2001)