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Article
Open AccessPan-cancer analysis and the oncogenic role of Glypican 1 in hepatocellular carcinoma
Recent studies indicate that Glypican 1 (GPC-1) is aberrantly expressed and plays a key role in certain cancers, but little is known in the hepatocellular carcinoma. Raw data from TCGA, GTEx and TIMER database...
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Article
White matter hyperintensities in cholinergic pathways correlates of cognitive impairment in moyamoya disease
To investigate the effect of cholinergic pathways damage caused by white matter hyperintensities (WMHs) on cognitive function in moyamoya disease (MMD).
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Article
In vitro anticancer study of novel curcumin derivatives via targeting PI3K/Akt/p53 signaling pathway
Four new series of curcumin derivatives bearing NO-donating moiety were synthesized via etherification, nucleophilic substitution, and Knoevenagel condensation etc. The cytotoxicity activity of curcumin derivativ...
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Article
Ziprasidone population pharmacokinetics and co-medication effects in Chinese patients
Ziprasidone is widely used in the treatment of psychiatric disorders. Despite its prevalence, there is a notable lack of population pharmacokinetics (PPK) studies on ziprasidone in serum, both domestically and...
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Article
Silybin attenuates avermectin-induced oxidative damage in carp respiration by modulating the cGAS-STING pathway and endoplasmic reticulum stress
Avermectin is a commonly used insect repellent for aquaculture and crops, but it is easy to remain in the aquatic environment, causing organism disorders, inflammation, and even death. This resulted in signifi...
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Article
Mitochondrial Uncoupling Protein-2 Ameliorates Ischemic Stroke by Inhibiting Ferroptosis-Induced Brain Injury and Neuroinflammation
Ischemic stroke is a devastating disease in which mitochondrial damage or dysfunction substantially contributes to brain injury. Mitochondrial uncoupling protein-2 (UCP2) is a member of the UCP family, which r...
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Article
Harnessing key bacteria from suppressive soil to mitigate banana Panama disease
Soil microbiomes play a pivotal role in sha** plant health and their ability to suppress the pathogens. However, the specific microbial features that confer disease suppression in agricultural soils have rem...
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Article
Soil nutrient levels are associated with suppression of banana Fusarium wilt disease
Disease-suppressive soils exhibit enhanced soil nutrient status.
Soil available phosphorus is a distinct feature of disease-...
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Article
Jasme-C: mechanistic study of periodic nanoporous graphene salt-rejection membranes for seawater desalination
The global shortage of freshwater resources is becoming increasingly rigorous, with more than 300 million people no longer able to sustain a normal life. Currently, two-dimensional (2D) nanoporous materials ar...
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Article
Open AccessAnalysis of risk factors for acute kidney injury in children with severe wasp stings
Acute kidney injury (AKI) is common in children with sepsis, chronic kidney disease, poisoning or other conditions. Wasp stings are recognized as an important etiology. Several retrospective studies have inves...
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Article
Open AccessAssociation between risk of preterm birth and long-term and short-term exposure to ambient carbon monoxide during pregnancy in chongqing, China: a study from 2016-2020
Preterm birth (PTB) is an important predictor of perinatal morbidity and mortality. Previous researches have reported a correlation between air pollution and an increased risk of preterm birth. However, the sp...
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Article
Open AccessSpike-based dynamic computing with asynchronous sensing-computing neuromorphic chip
By mimicking the neurons and synapses of the human brain and employing spiking neural networks on neuromorphic chips, neuromorphic computing offers a promising energy-efficient machine intelligence. How to bor...
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Article
Open AccessEffect of fence tray matching care on excess adhesive and bracket placement accuracy for orthodontic bonding: an in vitro study
This study aimed to evaluate the effect of fence tray matching care (FTMC) in bracket bonding by measuring excess adhesive, as well as linear and angular deviations, and by comparing it with the half-wrapped t...
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Article
Open AccessMXene-based flexible electronic materials for wound infection detection and treatment
Wound infection is a worldwide health issue that not only brings large detrimental effects to people’s physical and mental health, but also causes substantial economic burdens to society. By using traditional ...
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Article
Compensatory effects of loneliness: how and when does workplace loneliness promote employees unethical pro-organizational behavior
With the development of information and communication technology (ICT) and the rise of telecommuting, loneliness has become a prevalent emotional experience in the workplace. Therefore, it is important to unde...
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Article
Graphene-based magnetically tunable multi-band terahertz absorber with switchable frequency
A magnetically tunable multi-band switchable frequency terahertz (THz) absorber based on graphene is proposed, and its absorption performance is analyzed using the
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Article
Enhanced Removal of Potassium, Sodium, and Lead During the Iron Ore Sintering Process
In this study, a mixture rich in K, Na, and Pb, composed of undesired elements rich iron ore A, sinter dust, and blast furnace dust (ore-dust mix,), is sintered along with the regular iron ore. The K, Na, and ...
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Article
Gypenoside XLIX Activates the Sirt1/Nrf2 Signaling Pathway to Inhibit NLRP3 Inflammasome Activation to Alleviate Septic Acute Lung Injury
Currently, treatment options for acute lung injury (ALI) are limited. Gypenoside XLIX (Gyp-XLIX) is known for its anti-inflammatory properties, but there is a lack of extensive research on its effects against ...
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Article
Four-birds-with-one-stone: A multifunctional Ti-based material for solar-driven water evaporation
Sustainable, environmentally friendly and low-energy desalination materials have important research value for the increasing demand of freshwater year by year. However, it is a huge challenge to maintain high ...
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Article
Liquid–liquid phase separation of TZP promotes PPK-mediated phosphorylation of the phytochrome A photoreceptor
Phytochrome A (phyA) is the plant far-red (FR) light photoreceptor and plays an essential role in regulating photomorphogenic development in FR-rich conditions, such as canopy shade. It has long been observed ...
