1,391 Result(s)
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Yang YU
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Article
Acetylcytidine modification of Amotl1 by N-acetyltransferase 10 contributes to cardiac fibrotic expansion in mice after myocardial infarction
Cardiac fibrosis is a pathological scarring process that impairs cardiac function. N-acetyltransferase 10 (Nat10) is recently identified as the key enzyme for the N4-acetylcytidine (ac4C) modification of mRNAs...
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Open AccessGraphMriNet: a few-shot brain tumor MRI image classification model based on Prewitt operator and graph isomorphic network
Brain tumors are regarded as one of the most lethal forms of cancer, primarily due to their heterogeneity and low survival rates. To tackle the challenge posed by brain tumor diagnostic models, which typically...
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Open AccessIntraoperative urinary tract resection and construction in CRS + HIPEC procedures: a single center retrospective analysis
The safety and efficacy of CRS + HIPEC combined with urinary tract resection and reconstruction are controversial. This study aims to summarize the clinicopathological features and to evaluate the safety and s...
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Open AccessHypertension and cardiac damage in pheochromocytoma and paraganglioma patients: a large-scale single-center cohort study
Hypertension (HT) is one of the most common manifestations in patients with catecholamine-secreting neuroendocrine tumors. Although the cardiovascular manifestations of these tumors have been described, there ...
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Article
Effect of Temperature on the Mechanical Properties, Conductivity, and Microstructure of Multi-layer Graphene/Copper Composites Fabricated by Extrusion
Copper and copper alloys are widely used in electrical, rail transit and many other fields with their excellent electric, thermal conductivity and plasticity. However, pure copper has low strength and softenin...
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Open AccessSyrosingopine and UK5099 synergistically suppress non-small cell lung cancer by activating the integrated stress response
Non-small cell lung cancer (NSCLC) presents a global health challenge due to its low five-year survival rates, underscoring the need for novel therapeutic strategies. Our research explored the synergistic mech...
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Open AccessAutophagy-related molecular clusters identified as indicators for distinguishing active and latent TB infection in pediatric patients
Autophagy is crucial for controlling the manifestation of tuberculosis. This study intends to discover autophagy-related molecular clusters as biomarkers for discriminating between latent tuberculosis (LTBI) a...
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Open AccessA Phase 3, Multicenter, Randomized, Double-Blind, Placebo-Controlled 14-Week Study of Mirogabalin in Chinese Patients with Diabetic Peripheral Neuropathic Pain
There is no approved effective drug for diabetic peripheral neuropathic pain (DPNP) in China. Gabapentinoids including mirogabalin have shown promise, although data in Chinese patients are scarce.
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Open AccessExtraction and evaluation of cable forces of a cable-stayed bridge based on amplitude and phase estimation method
In order to identify the time-varying frequency and amplitude of structural vibration based on the bridge structural health monitoring data and obtain the cable force of cable-stayed bridges in real time, a sp...
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Open AccessQuantitative evaluation of bolt pre-load using coda wave interferometry and nonlinear coda wave interferometry: a comparative study
The quantitative evaluation of bolt pre-load is crucial for the maintenance and prevention of accidents in bolt-connected structures. This study introduces the coda wave interferometry (CWI) method and the non...
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Open AccessSinomenine treats rheumatoid arthritis by inhibiting MMP9 and inflammatory cytokines expression: bioinformatics analysis and experimental validation
Rheumatoid arthritis (RA) is a chronic systemic autoimmune disease marked by inflammatory cell infiltration and joint damage. The Chinese government has approved the prescription medication sinomenine (SIN), a...
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Author Correction: Transboundary cooperation in infrastructure operation generates economic and environmental co-benefits in the Lancang-Mekong River Basin
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Correction: Combined inhibition of JAK2-STAT3 and SMO-GLI1/tGLI1 pathways suppresses breast cancer stem cells, tumor growth, and metastasis
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A Robust Focused-and-Deconvolved Conventional Beamforming for a Uniform Linear Array
In the field of array signal processing, uniform linear arrays (ULAs) are widely used to detect/separate a weak target and estimate its direction of arrival from interference and noise. Conventional beamformin...
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Overexpression of TRIM44 mediates the NF-κB pathway to promote the progression of ovarian cancer
Ovarian cancer (OC) is the second most commonly seen cancer in the US, and patients with OC are commonly diagnosed in the advanced stage. Research into the molecular mechanisms and potential therapeutic target...
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Injectable ultrasonic sensor for wireless monitoring of intracranial signals
Direct and precise monitoring of intracranial physiology holds immense importance in delineating injuries, prognostication and averting disease1. Wired clinical instruments that use percutaneous leads are accurat...
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Preparation of millimeter-sized spherical SiO2–Al2O3 with various acid catalysts for the acetalization of glycerol with acetone
Through the sol-gel-oil ammonia column method, millimeter-sized spherical SiO2–Al2O3 particles were successfully prepared using aluminum isopropoxide and varying amounts of tetraethyl orthosilicate. The impact of...
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Transboundary cooperation in infrastructure operation generates economic and environmental co-benefits in the Lancang-Mekong River Basin
The Lancang-Mekong River Basin is facing booming water resources infrastructure development, long-term transboundary conflicts and trade-offs between economic goals and ecosystem services provision. Optimizing...
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Open AccessSpatially covariant gravity with nonmetricity
Scalar fields play an important role in constructing modified gravity theories. In the case of a single scalar field with timelike gradient, the corresponding Lagrangian in the unitary gauge takes the form of ...
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Prognostic factors for residual symptoms following percutaneous endoscopic lumbar discectomy
To explore the risk factors for residual symptoms following percutaneous endoscopic lumbar discectomy (PELD). A retrospective case-controlled study. From January 2015 to December 2020, consecutive patients who...
