46 Result(s)
within
Yanfei Chen
English
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Article
Open AccessLongitudinal gut fungal alterations and potential fungal biomarkers for the progression of primary liver disease
Liver disease, a major health concern worldwide, is a serious and progressive disorder. Herein, we not only established a mouse model of DEN+CCl4-induced primary liver disease but also collected clinical human sa...
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Typical lake area is accurately predicted and assessed based on deep learning algorithms and associated physical mechanisms
Accurate quantification of lake areas is pivotal for understanding regional hydrological cycles and conserving wetlands. Existing methodologies, including remote sensing interpretations and conventional deep l...
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A novel learning method for feature evolvable streams
Recently, many researchers have focused on a novel type of data stream known as a feature evolvable stream, wherein the existing features may become obsolete while new features emerge simultaneously. The occur...
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Open AccessInterpretable machine learning in predicting drug-induced liver injury among tuberculosis patients: model development and validation study
The objective of this research was to create and validate an interpretable prediction model for drug-induced liver injury (DILI) during tuberculosis (TB) treatment.
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Open AccessDevelopment and characterization of a novel nanobody with SRMV neutralizing activity
Peste des petits ruminants (PPR) is an acute, contact infectious disease caused by the small ruminant morbillivirus (SRMV), and its morbidity in goats and sheep can be up to 100% with significant mortality. Na...
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Correction to: Clinical Significance and Influencing Factors of Microvascular Tissue Reperfusion After Macrovascular Recanalization
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Open AccessWhole-exome sequencing analysis identifies novel variants associated with Kawasaki disease susceptibility
Kawasaki disease (KD) is an acute pediatric vasculitis affecting genetically susceptible infants and children. Although the pathogenesis of KD remains unclear, growing evidence links genetic susceptibility to ...
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Article
Prospects for Nerve Regeneration and Gene Therapy in the Treatment of Traumatic Brain Injury
Traumatic brain injury (TBI) is a prevalent neurological disorder and a leading cause of death and disability worldwide. The high mortality rates result in a tremendous burden on society and families in terms ...
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Clinical Significance and Influencing Factors of Microvascular Tissue Reperfusion After Macrovascular Recanalization
The relevance of impaired microvascular tissue reperfusion despite successful macrovascular angiographic reperfusion (no-reflow) in acute ischemic stroke (AIS) remains controversial. In this study, we aimed to...
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Influence of Post-weld Tempering Pulse on Microstructure and Mechanical Properties of NDM2 Rare Earth Magnesium Alloy Joint Welded by Resistance Spot Welding
Magnesium alloys are more and more applied to the field of automobile manufacturing because of their many excellent properties. However, defects such as cracks and shrinkage cavities are easy to form during th...
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Effects of Void Defects on Fracture Features and Tensile Strength of C/SiC Composites: an Image-based FEM Study
Manufacturing defects in ceramic matrix composites (CMCs), such as voids, microcracks, etc., significantly affect the damage events and strength of the materials. This study aims to reveal the effect of void d...
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Open AccessHigh-entropy rare-earth zirconate ceramics with low thermal conductivity for advanced thermal-barrier coatings
The high-entropy rare-earth zirconate ((La0.2Nd0.2Sm0.2Gd0.2Yb0.2)2Zr2O7, 5RE2Zr2O7 HEREZs) ceramics were successfully prepared by a new high-speed positive grinding strategy combined with solid-state reaction me...
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Open AccessHuman menstrual blood-derived stem cell transplantation suppresses liver injury in DDC-induced chronic cholestasis
Cholestatic liver injury can lead to serious symptoms and prognoses in the clinic. Currently, an effective medical treatment is not available for cholestatic liver injury. Human menstrual blood-derived stem ce...
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Open AccessA novel prognostic model based on single-cell RNA sequencing data for hepatocellular carcinoma
The tumour heterogeneous make-up of immune cell infiltrates is a key factor for the therapy response and prognosis of hepatocellular carcinoma (HCC). However, it is still a major challenge to comprehensively u...
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Review on mechanics of ultra-high-temperature materials
Ultra-high-temperature materials have applications in aerospace and nuclear industry. They are usually subjected to complex thermal environments during service. The mechanical properties of materials in ultra-...
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Open AccessOne-year follow-up of chest CT findings in patients after SARS-CoV-2 infection
Knowledge about the 1-year outcome of COVID-19 is limited. The aim of this study was to follow-up and evaluate lung abnormalities on serial computed tomography (CT) scans in patients with COVID-19 after hospit...
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Achieving air pollutant emission reduction targets with minimum abatement costs: An enterprise-level allocation method with constraints of fairness and feasibility
For achieving air pollutant emission reduction targets, total pollutant amount control is being continuously promoted in China. However, the traditional pattern of pollutant emission reduction allocation regar...
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Open AccessGut mycobiota alterations in patients with COVID-19 and H1N1 infections and their associations with clinical features
The relationship between gut microbes and COVID-19 or H1N1 infections is not fully understood. Here, we compared the gut mycobiota of 67 COVID-19 patients, 35 H1N1-infected patients and 48 healthy controls (HC...
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Carotid Endarterectomy and Stenting in a Chinese Population: Safety Outcome of the Revascularization of Extracranial Carotid Artery Stenosis Trial
Carotid endarterectomy (CEA) and carotid artery stenting (CAS) have been well-established as two effective treatment modalities for carotid artery stenosis, while their clinical outcomes in real-world China ar...
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Open AccessPositive regulation of Type III secretion effectors and virulence by RyhB paralogs in Salmonella enterica serovar Enteritidis
Small non-coding RNA RyhB is a key regulator of iron homeostasis in bacteria by sensing iron availability in the environment. Although RyhB is known to influence bacterial virulence by interacting with iron me...
