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Article
Concurrent multiscale topology optimization of hollow structures considering geometrical nonlinearity
Lattice materials and hollow structures possess excellent mechanical properties, which are beneficial to satisfy the lightweight demands of the products, especially for the large deformation situation. Therefo...
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Article
Non-isothermal crystallization kinetics of biodegradable regenerated poly(butylene carbonate-co-terephthalate) copolyesters based on post-consumer polyester fabrics
The regenerated poly(butylene carbonate-co-terephthalate) (r-PBCT) copolyesters based on post-consumer polyester fabrics with similar intrinsic viscosity were synthesized via a two-step melt polycondensation meth...
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Article
Open AccessNasal splinting and mouth breathing training reduce emergence delirium after endoscopic sinus surgery: a randomized controlled trial
Emergence delirium (ED) is generally occurred after anesthesia associated with increased risks of long-term adverse outcomes. Therefore, this study aimed to evaluate the efficacy of preconditioning with nasal ...
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Article
Multigram-scale synthesis of GS-4997, an inhibitor of apoptosis signal-regulating kinase 1
This paper describes the development of a practical, efficient and reproducible preparation of ASK1 inhibitor GS-4997 (Selonsertib). Our efforts were committed to designing and develo** a novel synthetic strate...
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Article
MATLAB implementations for 3D geometrically nonlinear topology optimization: 230-line code for SIMP method and 280-line code for MMB method
Topology optimization can generate the innovative material layout to meet the performance demands. Meanwhile, the computational programs with educational purposes were also released for topology optimization. ...
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Article
Flavobacterium potami sp. nov., a multi-metal resistance genes harbouring bacterium isolated from shallow river silt
Environmental pollution by heavy metals is becoming an increasing problem and has become a matter of great concern due to the adverse effects worldwide. In this study, we report a novel strain of multi-metal r...
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Article
The Mechanism Underlying the Regulation of Long Non-coding RNA MEG3 in Cerebral Ischemic Stroke
Cerebral ischemic stroke is one of the leading causes of morbidity and mortality worldwide, and rapidly increasing annually with no more effective therapeutic measures. Thus, the novel diagnostic and prognosti...
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Article
Hollow structural topology optimization considering geometrical nonlinearity using three-dimensional moving morphable bars
Hollow structures show higher performance and more easily satisfy lightweight requirements than solid structures in engineering. However, hollow optimized results obtained by topology optimization are currentl...
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Article
Dietary exposure and risk assessment of chlorinated paraffins in roots and rhizomes of traditional Chinese medicine herbs
Traditional Chinese medicine (TCM) provides therapeutic and health care effects through dietary intake. Owing to the susceptibility of plants to contaminations, a risk assessment system is urgently needed to e...
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Article
Authentication of the Geographical Origin of Shandong Scallop Chlamys farreri Using Mineral Elements Combined with Multivariate Data Analysis and Machine Learning Algorithm
Geographical traceability of seafood is a global concern for both consumers and importers. It is urgent to develop a scientific approach for identifying the geographic origin of seafood to combat labeling frau...
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Article
Multigram-scale synthesis of GSK 2,256,294, an inhibitor of soluble epoxide hydrolase in clinical evaluation
This paper described the development of an improved, practical and efficient protocol method for the multigram-scale synthesis of GSK 2,256,294, an orally bioavailable potent and selective inhibitor of sEH. Th...
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Chapter and Conference Paper
Review of Wind Power Grid Connection Technology
Under the background of carbon peak and carbon neutral target, clean renewable energy such as wind power becomes inevitable for development. Wind power generation has the advantages of convenient development, ...
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Article
A new method of extracting L-quebrachitol from serum obtained from acid coagulation of natural rubber latex
A cost-efficient way of extracting L-quebrachitol from NR (natural rubber) latex was developed, and the efficiency in extracting L-quebrachitol with two different liquid–liquid extraction system was compared i...
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Article
Composition properties of rubber from parts of Taraxacum Kok-saghyz roots
Dandelion (Taraxacum mongolicum) is known as a perennial herbaceous plant belonging to the Asteraceae family. Its rhizome contains a lot of rubber. Adopting three different methods, namely the nucleobase metho...
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Article
Open AccessHigh dose and hepatobiliary dysfunction are associated with hand-foot syndrome in patients with lymphoma using pegylated liposomal doxorubicin: a retrospective study
In clinical practice, the risk factors for pegylated liposomal doxorubicin-related hand-foot syndrome remain unclear. The purpose of this study was to determine the risk factors associated with hand-foot syndr...
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Article
UTX condensation underlies its tumour-suppressive activity
UTX (also known as KDM6A) encodes a histone H3K27 demethylase and is an important tumour suppressor that is frequently mutated in human cancers1. However, as the demethylase activity of UTX is often dispensable f...
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Article
Topology optimization of thin-walled cross section using moving morphable components approach
Thin-walled beams are extensively applied in the engineering structures, in which the conceptual design of cross-sectional shape and topology is the most important issue. Traditional topology optimization meth...
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Article
Open AccessRisk factors for pegylated liposomal doxorubicin-induced moderate to severe hand-foot syndrome in breast cancer patients: assessment of baseline clinical parameters
Hand-foot syndrome (HFS) is a side effect of skin related to pegylated liposomal doxorubicin (PLD) application. Moderate to severe hand-foot syndrome (MSHFS) might have a serious impact on patients’ quality of...
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Article
A low-background fluorescent aptasensor for acetamiprid detection based on DNA three-way junction-formed G-quadruplexes and graphene oxide
A simple fluorescence detection platform has been established for acetamiprid assay based on DNA three-way junctions (TWJs), which can triple the fluorescence signal without any other amplification. It is desi...
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Article
Hyperaccumulation of cadmium by scallop Chlamys farreri revealed by comparative transcriptome analysis
Cadmium (Cd) is a hazardous environmental contaminant, which has a serious effect on the ecosystem, food safety and human health. Scallop could accumulate high concentration of Cd from the environment and has ...
