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Article
Open AccessA powerful on line ABTS+–CE-DAD method to screen and quantify major antioxidants for quality control of Shuxuening Injection
A novel method of on-line 2,2′-Azinobis-(3-ethylbenzthiazoline-6-sulphonate)-Capillary Electrophoresis-Diode Array Detector (on-line ABTS+-CE-DAD) was developed to screen the major antioxidants from complex herba...
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Article
Open AccessThe pharmacokinetics, bioavailability and excretion of bergapten after oral and intravenous administration in rats using high performance liquid chromatography with fluorescence detection
A sensitive, specific, reproducible and optimized high performance liquid chromatography with fluorescence detection (HPLC-FLD) method for the determination of bergapten in rat plasma was established and appli...
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Article
Separation and stacking of iodine species from seafood using surfactant-coated multiwalled carbon nanotubes as a pseudo-stationary phase in capillary electrophoresis
This article describes an on-line technique for hydrodynamic injections of long sample plugs with simultaneous stacking of iodine species in capillary electrophoresis (CE) with diode array detection. Surfactan...
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Article
Open AccessLC–MS/MS determination and pharmacokinetic study of columbianadin in rat plasma after intravenous administration of pure columbianadin
Columbianadin, one of the active coumarins, is isolated from Radix Angelicae pubescentis which has been used as a traditional Chinese medicine for the treatment of rheumatic diseases for thousands of years. A fas...
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Article
Pharmacokinetics study of asperosaponin VI and its metabolites cauloside A, HN saponin F and hederagenin
This experiment's with aim was to study the pharmacokinetics of asperosaponin VI and its three metabolites (cauloside A, HN saponin F and hederagenin) via a sensitive high performance liquid chromatography co...
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Article
Quantitative Determination of Anti-Inflammatory Columbianetin in Rat Plasma by LC-ESI-MS/MS for Pharmacokinetic Studies after Oral Administration of Duhuo Extract
Specific LC-ESI-MS/MS method or procedure was developed and validated for columbianetin quantification in rat plasma using epicatechin as an internal standard (IS). Chromatographic separation was performed on ...
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Article
A Rapid Method for Qualitative and Quantitative Analysis of Major Constituents in Dengzhanxixin Injection by LC-DAD-ESI–MSn
For the first time a rapid method for qualitative and quantitative analysis of constituents in Dengzhanxixin injection was established by liquid chromatography with electrospray ionization–tandem mass spectrom...
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Article
Determination of Phenolic Acids in Danshen Preparations by LC with Chemiluminescence Detection
A simple and sensitive method has been developed for the simultaneous determination of eight phenolic acids in Danshen preparations based on liquid chromatography with chemiluminescence detection. Chemilumines...