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Article
Open AccessNLRP4E regulates actin cap formation through SRC and CDC42 during oocyte meiosis
Members of the nucleotide-binding oligomerization domain, leucine rich repeat and pyrin domain containing (NLRP) family regulate various physiological and pathological processes. However, none have been shown ...
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Article
Open AccessIntegrative analyses of bulk and single-cell transcriptomics reveals the infiltration and crosstalk of cancer-associated fibroblasts as a novel predictor for prognosis and microenvironment remodeling in intrahepatic cholangiocarcinoma
Intrahepatic cholangiocarcinoma (ICC) is a highly malignant neoplasm and characterized by desmoplastic matrix. The heterogeneity and crosstalk of tumor microenvironment remain incompletely understood.
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Article
Open AccessA multi-center cross-sectional study of Chinese Herbal Medicine-Drug adverse reactions using active surveillance in Singapore’s Traditional Chinese Medicine clinics
This study aimed to investigate the rates and causality of patient-reported adverse events (AEs) associated with concomitant Chinese Herbal Medicine (CHM) and Western Medicine prescription drug (WMPD) consumpt...
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Article
The Relationships Between Danxia Geoheritages and Regional Tectonics in Southern Sichuan Basin: Implications for the Spatial Distribution of Danxia Landforms in China
The Danxia geoheritage has emerged as a compelling subject of study, while the Tethys-Himalayan tectonic domain continues to captivate scholarly attention. However, a noteworthy gap exists in the literature co...
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Article
Open AccessAssociation of antenatal corticosteroids with mortality and morbidities in very preterm infants born to women with hypertensive disorders of pregnancy: a multicenter prospective cohort study
Hypertensive disorders of pregnancy (HDP) is the most common cause of indicated preterm delivery, but the impact of prenatal steroid exposure on the outcomes of preterm infants born to HDP mothers, who may be ...
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Chapter and Conference Paper
Exploration on an Advanced Knowledge Originated Online Course and Its Teaching Model for Innovative Talents Cultivation on Autonomous Unmanned Systems
With the rapid development of science and technology, the cultivation of innovative talents become increasingly important for the future of unmanned system industry. Although a lot of research and reform have ...
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Article
Open AccessSafety and Effectiveness of Baricitinib in Chinese Patients with Moderate-to-Severe Rheumatoid Arthritis: 24-Week Results from a Post-Marketing Safety Study
Baricitinib, a JAK1/JAK2 inhibitor, is approved for treatment of moderate-to-severe rheumatoid arthritis (RA) in China. This single-arm, prospective, multi-center, post-marketing safety study (PMSS) evaluated ...
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Article
Open AccessPrevalence of insomnia and its association with quality of life in caregivers of psychiatric inpatients during the COVID-19 pandemic: a network analysis
Studies on sleep problems among caregivers of psychiatric patients, especially during the COVID-19 pandemic, are limited. This study examined the prevalence and correlates of insomnia symptoms (insomnia hereaf...
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Article
Chlorinated Perylene Monoimide Monoanhydrate Synthesized via Hydrolysis and Its Application in Organic Solar Cells
Perylene-3,4-(dicarboxylic monoimide)-9,10-(dicarboxylic monoanhydrate) (PIA) is one key intermediate to construct functionalized perylene diimides (PDIs) for various applications. However, the difficulty in s...
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Article
Open AccessInternet addiction and residual depressive symptoms among clinically stable adolescents with major psychiatric disorders during the COVID-19 pandemic: a network analysis perspective
To assess the inter-relationships between residual depressive symptoms (RDS) and Internet addiction (IA) using network analysis among clinically stable adolescents with major psychiatric disorders during the C...
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Article
Open AccessLonger duration of initial invasive mechanical ventilation is still a crucial risk factor for moderate-to-severe bronchopulmonary dysplasia in very preterm infants: a multicentrer prospective study
We aimed to evaluate the risk factors for moderate-to-severe bronchopulmonary dysplasia (BPD) and focus on discussing its relationship with the duration of initial invasive mechanical ventilation (IMV) in very...
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Article
Model Test on Flow Field Characteristics of the Combined Complementary Double-Hole Network Ventilation with Shaft
The ventilation system significantly influences tunnel operation safety, energy savings, and reduced consumption. The Ying'erling highway tunnel proposed a hybrid ventilation system combined with complementary...
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Article
Analysis of Chinese Medical Syndrome Features of Ischemic Stroke Based on Similarity of Symptoms Subgroup
To derive the Chinese medicine (CM) syndrome classification and subgroup syndrome characteristics of ischemic stroke patients.
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Article
Exploring the potential anti-Alzheimer disease mechanisms of Alpiniae Oxyphyliae Fructus by network pharmacology study and molecular docking
Alpiniae Oxyphyliae Fructus (AOF) (yizhi) is a frequently medicated Chinese herb for Alzheimer disease (AD) treatment. The present study investigated the components and potential mechanisms of AOF through network...
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Article
Open AccessEffect of Vanadium Nitride (VN) Particles on Microstructure and Mechanical Properties of Extruded AZ31 Mg Alloy
The effect of vanadium nitride (VN) particles additives on microstructure and mechanical properties of the extruded AZ31 Mg alloy was systematically investigated. The experimental results revealed that the add...
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Chapter and Conference Paper
A Reinforcement-Learning-Driven Bees Algorithm for Large-Scale Earth Observation Satellite Scheduling
The Earth Observation Satellite Scheduling Problem (EOSSP) is difficult to solve due to its scale and constraints. Through analysing the problem, we build a mathematical programming model of the EOSSP. After t...
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Chapter and Conference Paper
A Novel Multi-task Model Imitating Dermatologists for Accurate Differential Diagnosis of Skin Diseases in Clinical Images
Skin diseases are among the most prevalent health issues, and accurate computer-aided diagnosis methods are of importance for both dermatologists and patients. However, most of the existing methods overlook th...
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Article
Open AccessEstimating disability-adjusted life years for breast cancer and the impact of screening in female populations in China, 2015–2030: an exploratory prevalence-based analysis applying local weights
Most cancer disability-adjusted life year (DALY) studies worldwide have used broad, generic disability weights (DWs); however, differences exist among populations and types of cancers. Using breast cancer as e...
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Article
Open AccessThe population-level economic burden of liver cancer in China, 2019–2030: prevalence-based estimations from a societal perspective
Benchmark data on the population-level economic burden are critical to inform policymakers about liver cancer control. However, comprehensive data in China are currently limited.
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Article
Oxygen-deficient NiCo2O4 nanowires as the robust cathode for high-performance nickel–zinc batteries
In this work, NiCo2O4 nanowires on carbon cloth are successfully fabricated by a simple two-step method hydrothermal and subsequent annealing under different gas (air and N2, respectively named A-NiCo2O4 and N-Ni...
