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  1. Article

    Open Access

    Integrated physiological, metabolomic, and transcriptomic analyses elucidate the regulation mechanisms of lignin synthesis under osmotic stress in alfalfa leaf (Medicago sativa L.)

    Alfalfa, an essential forage crop known for its high yield, nutritional value, and strong adaptability, has been widely cultivated worldwide. The yield and quality of alfalfa are frequently jeopardized due to ...

    **g Yang, Jiangnan Yi, Shihai Ma, Yafang Wang, Jiaxing Song, Shuo Li in BMC Genomics (2024)

  2. Article

    Open Access

    Structure-aware deep model for MHC-II peptide binding affinity prediction

    The prediction of major histocompatibility complex (MHC)-peptide binding affinity is an important branch in immune bioinformatics, especially helpful in accelerating the design of disease vaccines and immunity...

    Ying Yu, Lipeng Zu, Jiaye Jiang, Yafang Wu, Yinglin Wang, Midie Xu in BMC Genomics (2024)

  3. Article

    Open Access

    Genome-wide identification and bioinformatics analysis of the WD40 transcription factor family and candidate gene screening for anthocyanin biosynthesis in Rhododendron simsii

    WD40 transcription factors (TFs) constitute a large gene family in eukaryotes, playing diverse roles in cellular processes. However, their functions in the major ornamental plant, Rhododendron simsii, remain poor...

    Cheng Wang, Yafang Tang, Yan Li, Chao Hu, **gyi Li, Ang Lyu in BMC Genomics (2023)

  4. Article

    Open Access

    Genetic variants associated mRNA stability in lung

    Expression quantitative trait loci (eQTLs) analyses have been widely used to identify genetic variants associated with gene expression levels to understand what molecular mechanisms underlie genetic traits. Th...

    Jian-Rong Li, Mabel Tang, Yafang Li, Christopher I. Amos, Chao Cheng in BMC Genomics (2022)

  5. Article

    Open Access

    Genome-wide identification and functional analysis of circRNAs in Trichophyton rubrum conidial and mycelial stages

    Circular RNAs (circRNAs) are a group of noncoding RNAs that participate in gene expression regulation in various pathways. The essential roles of circRNAs have been revealed in many species. However, knowledge...

    **ngwei Cao, **ngye Xu, Jie Dong, Ying Xue, Lilian Sun, Yafang Zhu, Tao Liu in BMC Genomics (2022)

  6. Article

    Open Access

    Genome-wide imaging association study implicates functional activity and glial homeostasis of the caudate in smoking addiction

    Nearly 6 million deaths and over a half trillion dollars in healthcare costs worldwide are attributed to tobacco smoking each year. Extensive research efforts have been pursued to elucidate the molecular under...

    David C. Qian, David L. Molfese, Jennifer L. **, Alexander J. Titus in BMC Genomics (2017)

  7. Article

    Open Access

    The use of global transcriptional analysis to reveal the biological and cellular events involved in distinct development phases of Trichophyton rubrum conidial germination

    Conidia are considered to be the primary cause of infections by Trichophyton rubrum.

    Tao Liu, Qian Zhang, Lingling Wang, Lu Yu, Wenchuan Leng, Jian Yang in BMC Genomics (2007)

  8. Article

    Open Access

    Analysis of the dermatophyte Trichophyton rubrum expressed sequence tags

    Dermatophytes are the primary causative agent of dermatophytoses, a disease that affects billions of individuals worldwide. Trichophyton rubrum is the most common of the superficial fungi. Although T. rubrum is a...

    Lingling Wang, Li Ma, Wenchuan Leng, Tao Liu, Lu Yu, Jian Yang, Li Yang in BMC Genomics (2006)