45 Result(s)

Article

Landform and lithospheric development contribute to the assembly of mountain floras in China

Although it is well documented that mountains tend to exhibit high biodiversity, how geological processes affect the assemblage of montane floras is a matter of ongoing research. Here, we explore landform-spec...

Wan-Yi Zhao, Zhong-Cheng Liu, Shi Shi, Jie-Lan Li, Ke-Wang Xu… in Nature Communications (2024)

Article

Structural basis and synergism of ATP and Na⁺ activation in bacterial K⁺ uptake system KtrAB

The K⁺ uptake system KtrAB is essential for bacterial survival in low K⁺ environments. The activity of KtrAB is regulated by nucleotides and Na⁺. Previous studies proposed a putative gating mechanism of KtrB regu...

Wesley Tien Chiang, Yao-Kai Chang, Wei-Han Hui, Shu-Wei Chang… in Nature Communications (2024)

Article

Tumor-infiltrating immune cells and survival in head and neck squamous cell carcinoma: a retrospective computational study

The immune infiltration profiles of the tumor microenvironment have effects on the prognosis of head and neck squamous cell carcinoma (HNSCC). Whereas, HNSCC is a heterogeneous group of tumors, but past work h...

Lei Zhang, Wei-Quan Wang, Jun-Hong Chen, Jia Feng, Ya-Zhou Liao… in Scientific Reports (2024)

Article

Prussian blue analog with separated active sites to catalyze water driven enhanced catalytic treatments

Chemodynamic therapy (CDT) uses the Fenton or Fenton-like reaction to yield toxic ‧OH following H₂O₂ → ‧OH for tumoral therapy. Unfortunately, H₂O₂ is often taken from the limited endogenous supply of H₂O₂ in can...

Liu-Chun Wang, Pei-Yu Chiou, Ya-** Hsu, Chin-Lai Lee… in Nature Communications (2023)

Article

Rewired m⁶A epitranscriptomic networks link mutant p53 to neoplastic transformation

N6-methyladenosine (m⁶A), one of the most prevalent mRNA modifications in eukaryotes, plays a critical role in modulating both biological and pathological processes. However, it is unknown whether mutant p53 neom...

An Xu, Mo Liu, Mo-Fan Huang, Yang Zhang, Ruifeng Hu… in Nature Communications (2023)

Article

Development and characterization of novelly grown fire-resistant fungal fibers

This study conducted a comprehensive characterization and analyses on the fire-resistant behaviors of novel fungal fibers grown with substrate containing Silica (Si) source at multiple scales. At micro-scale, ...

**** Zhang, Yanjun Li, Xudong Fan, Gary Wnek, Ya-Ting T. Liao… in Scientific Reports (2022)

Article

Differential effects of macrophage subtypes on SARS-CoV-2 infection in a human pluripotent stem cell-derived model

Dysfunctional immune responses contribute critically to the progression of Coronavirus Disease-2019 (COVID-19), with macrophages as one of the main cell types involved. It is urgent to understand the interacti...

Qizhou Lian, Kui Zhang, Zhao Zhang, Fuyu Duan, Liyan Guo… in Nature Communications (2022)

Article

Author Correction: Elucidation of the core betalain biosynthesis pathway in Amaranthus tricolor

Yu-Cheng Chang, Yi-Ching Chiu, Nai-Wen Tsao, Yuan-Lin Chou… in Scientific Reports (2021)

Article

Ultrasound-guided corticosteroid injection for patients with carpal tunnel syndrome: a systematic review and meta-analysis of randomized controlled trials

Carpal tunnel syndrome (CTS) refers to the symptoms and signs caused by the compression of the median nerve in the carpal tunnel. It can be treated by corticosteroid injection into the carpal tunnel. Two metho...

Fu-An Yang, Ya-Chu Shih, Jia-Pei Hong, Chin-Wen Wu, Chun-De Liao… in Scientific Reports (2021)

Article

CpG-adjuvanted stable prefusion SARS-CoV-2 spike protein protected hamsters from SARS-CoV-2 challenge

The COVID-19 pandemic presents an unprecedented challenge to global public health. Rapid development and deployment of safe and effective vaccines are imperative to control the pandemic. In the current study, ...

Chia-En Lien, Yi-Jiun Lin, Charles Chen, Wei-Cheng Lian… in Scientific Reports (2021)

Article

Elucidation of the core betalain biosynthesis pathway in Amaranthus tricolor

Amaranthus tricolor L., a vegetable Amaranthus species, is an economically important crop containing large amounts of betalains. Betalains are natural antioxidants and can be classified into betacyanins and betax...

Yu-Cheng Chang, Yi-Ching Chiu, Nai-Wen Tsao, Yuan-Lin Chou… in Scientific Reports (2021)

Article

Effects of applying platelet-rich plasma during arthroscopic rotator cuff repair: a systematic review and meta-analysis of randomised controlled trials

Because of its healing properties, platelet-rich plasma (PRP) has been applied to the bone–tendon interface during arthroscopic rotator cuff repair to improve surgical outcomes. However, its effects remain amb...

Fu-An Yang, Chun-De Liao, Chin-Wen Wu, Ya-Chu Shih, Lien-Chen Wu… in Scientific Reports (2020)

Article

NT5C2 methylation regulatory interplay between DNMT1 and insulin receptor in type 2 diabetes

Epigenetics alternation of non-genetic variation and genome-wide association study proven allelic variants may associate with insulin secretion in type 2 diabetes (T2D) development. We analyzed promoter DNA me...

Yng-Tay Chen, Wei-De Lin, Wen-Ling Liao, Ya-Ching Tsai… in Scientific Reports (2020)

Article

SWATH-MS-based quantitative proteomics reveals a uniquely intricate defense response in Cnaphalocrocis medinalis-resistant rice

Cnaphalocrocis medinalis is a major insect pest of rice in Asia. A few defensive enzymes were reported to show higher activities in a resistant rice line (Qingliu) than in a susceptible rice line (TN1) upon leaff...

Boon Huat Cheah, Hou-Ho Lin, Han-Ju Chien, Chung-Ta Liao, Li-Yu D Liu… in Scientific Reports (2020)

Article

Chelating-agent-assisted control of CsPbBr₃ quantum well growth enables stable blue perovskite emitters

Metal halide perovskites have emerged as promising candidates for solution-processed blue light-emitting diodes (LEDs). However, halide phase segregation – and the resultant spectral shift – at LED operating v...

Ya-Kun Wang, Dongxin Ma, Fanglong Yuan, Kamalpreet Singh… in Nature Communications (2020)

Article

Identifying SARS-CoV-2-related coronaviruses in Malayan pangolins

The ongoing outbreak of viral pneumonia in China and across the world is associated with a new coronavirus, SARS-CoV-2¹. This outbreak has been tentatively associated with a seafood market in Wuhan, China, where ...

Tommy Tsan-Yuk Lam, Na Jia, Ya-Wei Zhang, Marcus Ho-Hin Shum, Jia-Fu Jiang… in Nature (2020)

Article

Classification of Early-Onset and Late-Onset Idiopathic Chronic Pancreatitis Needs Reconsideration

Bimodal classification of idiopathic chronic pancreatitis (ICP) into early-onset (<35 years) and late-onset (>35 years) ICP was proposed in 1994 based on a study of 66 patients. However, bimodal distribution w...

Yu Liu, Dan Wang, Yi-Li Cai, Tao Zhang, Hua-Liang Chen, Lu Hao… in Scientific Reports (2020)

Article

Environmental remodeling of human gut microbiota and antibiotic resistome in livestock farms

Anthropogenic environments have been implicated in enrichment and exchange of antibiotic resistance genes and bacteria. Here we study the impact of confined and controlled swine farm environments on temporal c...

Jian Sun, **ao-** Liao, Alaric W. D’Souza, Manish Boolchandani… in Nature Communications (2020)

Article

Genetic risk score for risk prediction of diabetic nephropathy in Han Chinese type 2 diabetes patients

We evaluated whether genetic information could offer improvement on risk prediction of diabetic nephropathy (DN) while adding susceptibility variants into a risk prediction model with conventional risk factors...

Li-Na Liao, Tsai-Chung Li, Chia-Ing Li, Chiu-Shong Liu, Wen-Yuan Lin… in Scientific Reports (2019)