1,315 Result(s)
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Article
Long-Term Survival and Recurrence Patterns in Locally Advanced Esophageal Squamous Cell Carcinoma Patients with Pathologic Complete Response After Neoadjuvant Chemotherapy Followed by Surgery
The higher pathologic complete response (pCR) after neoadjuvant chemoradiotherapy compared with neoadjuvant chemotherapy for locally advanced esophageal squamous cell carcinoma (ESCC) has not translated into s...
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Article
FXR activation remodels hepatic and intestinal transcriptional landscapes in metabolic dysfunction-associated steatohepatitis
The escalating obesity epidemic and aging population have propelled metabolic dysfunction-associated steatohepatitis (MASH) to the forefront of public health concerns. The activation of FXR shows promise to co...
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Research Progress of Vagal Nerve Regulation Mechanism in Acupuncture Treatment of Atrial Fibrillation
Atrial fibrillation (AF) is the most common arrhythmia in clinical practice. It has a high prevalence and poor prognosis. The application of antiarrhythmic drugs and even surgery cannot completely treat the di...
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Article
Partitions into Segal–Piatetski–Shapiro sequences
Let \(\kappa \) κ be any positive real number and
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Article
Open AccessThalamocortical functional connectivity and rapid antidepressant and antisuicidal effects of low-dose ketamine infusion among patients with treatment-resistant depression
Previous studies have shown an association between the thalamocortical dysconnectivity and treatment-resistant depression (TRD). Whether a single subanesthetic dose of ketamine may change thalamocortical conne...
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Constructing 2D bismuth-based heterostructure for highly efficient photocatalytic CO2 reduction
Reforming carbon dioxide (CO2) into fuels and valuable chemicals using solar energy holds significant potential for emission reduction and addressing energy supply challenges. The recombination of photocarriers r...
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Similar tolerance of urban birds towards both benign human and lethal cat predators
Prey animals make crucial escape decisions when confronted by predators. Previous research, predominantly employing human surrogates, has consistently shown that urban-dwelling prey exhibit greater tolerance f...
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Open AccessAssociation of early-term birth and breastfeeding practices with nutritional outcomes in singleton term infants: a multicenter cross-sectional study
Limited research has explored the associations of gestational age (GA) and breastfeeding practices with growth and nutrition in term infants.
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Open AccessArtificial Intelligence Application in Skull Bone Fracture with Segmentation Approach
This study aims to evaluate an AI model designed to automatically classify skull fractures and visualize segmentation on emergent CT scans. The model’s goal is to boost diagnostic accuracy, alleviate radiologi...
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Article
Insights into photocatalytic mechanism over a novel Cu2WS4/MoS2 S-scheme heterojunction
A novel efficient Cu2WS4/MoS2 step-scheme (S-scheme) heterojunction photocatalyst was constructed for the first time and applied in the removal of environmental pollutants. Among the as-prepared photocatalysts, t...
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Open AccessResearch on shock wave driving technology of methane explosion
In order to improve the driving ability of the explosion wave simulation equipment, reduce the erosion effect of condensed explosives on the explosion wave simulation equipment, improve the safety of the test ...
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Lethal pulmonary thromboembolism in mice induced by intravenous human umbilical cord mesenchymal stem cell-derived large extracellular vesicles in a dose- and tissue factor-dependent manner
Mesenchymal stem cell-derived extracellular vesicles (MSC-EVs) have obvious advantages over MSC therapy. But the strong procoagulant properties of MSC-EVs pose a potential risk of thromboembolism, an issue tha...
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Article
Glial growth factor 2 treatment alleviates ischemia and reperfusion-damaged integrity of the blood-brain barrier through decreasing Mfsd2a/caveolin-1-mediated transcellular and Pdlim5/YAP/TAZ-mediated paracellular permeability
The impairment of blood-brain barrier (BBB) integrity is the pathological basis of hemorrhage transformation and vasogenic edema following thrombolysis and endovascular therapy. There is no approved drug in th...
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A global survey on the use of the international classification of diseases codes for metabolic dysfunction-associated fatty liver disease
With the implementation of the 11th edition of the International Classification of Diseases (ICD-11) and the publication of the metabolic dysfunction-associated fatty liver disease (MAFLD) nomenclature in 2020...
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Article
Metabolome and Genome Analysis of a Novel Endophytic Fungus Aureobasidium pullulans KB3: Discovery of Polyketones and Polyketone Biosynthesis Pathway
Endophytic fungi associated with plants may contain undiscovered bioactive compounds. Under standard laboratory conditions, most undiscovered compounds are inactive, whereas their production could be stimulate...
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Open AccessDe novo design of a nanoregulator for the dynamic restoration of ovarian tissue in cryopreservation and transplantation
The cryopreservation and transplantation of ovarian tissue underscore its paramount importance in safeguarding reproductive capacity and ameliorating reproductive disorders. However, challenges persist in ovar...
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Article
T cell-redirecting antibody for treatment of solid tumors via targeting mesothelin
T cell engaging bispecific antibodies (TCBs) have recently become significant in cancer treatment. In this study we developed MSLN490, a novel TCB designed to target mesothelin (MSLN), a glycosylphosphatidylin...
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Article
Molecular Chain Flexibility and Dielectric Loss at High-Frequency: Impact of Ester Bond Arrangement in Poly(ester imide)s
The evolution of high-frequency communication has accentuated the significance of controlling dielectric properties in polymer media. Traditionally, it has been theorized that rigid molecular chains lead to lo...
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Effects of melancholic features on positive and negative suicidal ideation in patients with treatment-resistant depression and strong suicidal ideation receiving low-dose ketamine infusion
The role of melancholic features on the antisuicidal effect of 0.5 mg/kg ketamine infusion has remained unclear in patients with treatment-resistant depression (TRD) and strong suicidal ideation (SI). Whether ...
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Article
Fabrication of Tremella-Like Zn-Based Composite Coating with Improved Photocatalytic Degradation Performance and Robust Superhydrophobicity
In this paper, as-received Zn powder and as-prepared Zn@(ZnWO4/ZnO) core–shell powder were used as feedstocks for plasma spraying to prepare Zn-based composite coatings and nano-ZnO was co-deposited by chemical v...