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  1. No Access

    Article

    Peroxynitrite-induced protein nitration is responsible for renal mitochondrial damage in diabetic rat

    Oxidative stress, especially mediated by peroxynitrite (ONOO), plays a key role in diabetes. Mitochondria, as the generating source of ONOO-, may also be the major damaging target of ONOO-. Whether ONOO-induce...

    J. H. Liang, Y. N. Li, J. S. Qi PhD, X. X. Jia in Journal of Endocrinological Investigation (2010)

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    Article

    Peroxynitrite mediates high glucose-induced osteoblast apoptosis

    High glucose (HG) state is closely related to diabetic complications, and among these one main pathogenesis involves apoptosis of important functional cells. However, the mechanism of osteoblast (OB) apoptosis...

    J. S. Qi PhD, Y. N. Li, B. S. Zhang, T. Niu… in Journal of Endocrinological Investigation (2008)