21 Result(s)

Article

JPT2 in subclinical hypothyroidism-related miscarriage as a transcription co-factor: involvement of LEPR/STAT3 activation

Subclinical hypothyroidism (SCH) has been identified to be associated with implantation failure, in which the dysfunction of trophoblast cells is involved. In this study, the transcriptomics of aborted placent...

Y.-Y. Zhou, S.-Y. Zhao, F.-J. Huang… in Journal of Endocrinological Investigation (2024)

Article

Concurrent use of capecitabine with radiation therapy and survival in breast cancer (BC) after neoadjuvant chemotherapy

Capecitabine has been studied as a radiosensitizer, and our study seeks to examine the association of concurrent capecitabine/radiation therapy (RT) on event-free- (EFS) and overall survival (OS) in women with...

Y. L. Liu, C. Chin, B. Catanese, S. M. Lee, S. Zhan… in Clinical and Translational Oncology (2018)

Article

A splicing-regulatory polymorphism in DRD2 disrupts ZRANB2 binding, impairs cognitive functioning and increases risk for schizophrenia in six Han Chinese samples

The rs1076560 polymorphism of DRD2 (encoding dopamine receptor D2) is associated with alternative splicing and cognitive functioning; however, a mechanistic relationship to schizophrenia has not been shown. Here,...

O S Cohen, T W Weickert, J L Hess, L M Paish, S Y McCoy… in Molecular Psychiatry (2016)

Article

Increased risk of cardiovascular events in end-stage renal disease patients with osteoporosis: a nationwide population-based cohort study

We investigated the cardiovascular disease risk and mortality in end-stage renal disease (ESRD) patients. A total of 12,535 patients with ESRD undergoing incident dialysis were enrolled, 4,153 (33.13 %) of who...

T.-M. Yu, C.-L. Lin, K.-H. Shu, Y.-L. Liu, C.-H. Chen… in Osteoporosis International (2015)

Article

Prevalence of hypertension and associated risk factors in Dehui City of Jilin Province in China

To evaluate the prevalence, awareness, treatment and control of hypertension and its risk factors in Dehui City of Jilin Province in China. The study was performed among 3778 subjects (male=1787) in Dehui city...

Q Wei, J Sun, J Huang, H-Y Zhou, Y-M Ding, Y-C Tao, S-M He… in Journal of Human Hypertension (2015)

Article

Subcutaneous oxyntomodulin analogue administration reduces body weight in lean and obese rodents

To determine the efficacy of a long-acting oxyntomodulin (OXM) analogue, OXM6421, in inhibiting food intake and decreasing body weight in lean and diet-induced obese (DIO) rodents.

Y-L Liu, H E Ford, M R Druce, J S Minnion, B C T Field… in International Journal of Obesity (2010)

Article

Coordinated changes in energy intake and expenditure following hypothalamic administration of neuropeptides involved in energy balance

The hypothalamic control of energy balance is regulated by a complex network of neuropeptide-releasing neurons. Although the effect of these neuropeptides on individual aspects of energy homoeostasis has been ...

N M Semjonous, K L Smith, J R C Parkinson, D J L Gunner… in International Journal of Obesity (2009)

Article

The effects of pancreatic polypeptide on locomotor activity and food intake in mice

Pancreatic polypeptide (PP) has been shown to inhibit food intake in both rodents and humans. Acute peripheral administration of PP increases oxygen consumption in obese mice. To further investigate the functi...

Y-L Liu, N M Semjonous, K G Murphy, M A Ghatei… in International Journal of Obesity (2008)

Article

More evidence supports the association of PPP3CC with schizophrenia

Calcineurin is a calcium/calmodulin-dependent protein phosphatase composed of two subunits, a regulatory subunit of calcineurin B (CNB) and a catalytic subunit of calcineurin A (CNA). PPP3CC is the γ isoform of C...

Y L Liu, C S J Fann, C M Liu, C C Chang, W C Yang, S I Hung, S L Yu… in Molecular Psychiatry (2007)

Article

A retrospective study of the relationship between biomarkers of atherosclerosis and erectile dysfunction in 988 men

Erectile dysfunction (ED) is associated with clinical atherosclerosis and several atherosclerotic risk factors including smoking, hypertension, dyslipidemia, diabetes mellitus, obesity and sedentary lifestyle....

C B Eaton, Y L Liu, M A Mittleman, M Miner… in International Journal of Impotence Research (2007)

Article

Ghrelin alleviates cancer chemotherapy-associated dyspepsia in rodents

Purpose: Chemotherapy treatment may lead to delayed gastric emptying, early satiety, anorexia, nausea and vomiting, described collectively as the cancer-associated dyspepsia syndrome (CAD...

Y.-L. Liu, N. M. Malik, G. J. Sanger… in Cancer Chemotherapy and Pharmacology (2006)

Article

Effects of the cannabinoid CB1 receptor antagonist SR141716 on oxygen consumption and soleus muscle glucose uptake in Lep^ob/Lep^ob mice

To investigate the effect of SR141716, a selective CB1 receptor antagonist, on energy expenditure and on glucose uptake in isolated soleus muscle of Lep^ob/Lep^ob mice.

Y L Liu, I P Connoley, C A Wilson, M J Stock in International Journal of Obesity (2005)

Article

Chronic CNS administration of Agouti-related protein (Agrp) reduces energy expenditure

OBJECTIVE: To investigate whether the Agouti-related protein (Agrp), the melanocortin receptor antagonist, alters oxygen consumption, as a measure of energy expenditure.

C J Small, Y L Liu, S A Stanley, I P Connoley… in International Journal of Obesity (2003)

Article

Mechanism of the thermogenic effect of Metabolite 2 (BTS 54 505), a major pharmacologically active metabolite of the novel anti-obesity drug, sibutramine

OBJECTIVE: To investigate the pharmacological mechanisms underlying the induction of thermogenesis by Metabolite 2 (M2; BTS 54 505), a major pharmacologically active metabolite of the anti-obesity drug, sibutrami...

Y-L Liu, DJ Heal, MJ Stock in International Journal of Obesity (2002)

Article

Retinoid X receptor agonists have anti-obesity effects and improve insulin sensitivity in Zucker fa/fa rats

OBJECTIVE: To investigate whether retinoid X receptor agonists act as insulin sensitizers and compare their effects with that of thiazolidinedione BRL 49653 in obese Zucker rats.

Y-L Liu, MV Sennitt, DC Hislop, DL Crombie, RA Heyman… in International Journal of Obesity (2000)

Article

A Chinese case of hereditary xanthinuria

T. -S. Chu, Y. -L. Liu, T. -S. Yen in Journal of Inherited Metabolic Disease (1993)