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Article
Structure of plasma-sprayed oxides in the MgO-Al2O3-SiO2 system
Cordierite (2MgO · 2Al2O3-SiO2), forsterite (2MgO · SiO2) and spinel (MgO · Al2O3) were rapidly solidified into a thick film through plasma spraying. The crystal structure of the assprayed deposits was examined u...
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Article
Expression of different conformations of p53 in the blast cells of acute myeloblastic leukaemia is related to in vitro growth characteristics
Expression of the wild-type p53 gene has an important role in cell differentiation, maturation and apoptosis. Mutation of the p53 gene is associated with tumour development and mutant p53 can promote cell prol...
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Article
Wild-type p53 is required for apoptosis induced by growth factor deprivation in factor-dependent leukaemic cells
The p53 gene is a growth control gene, abnormalities of which have been implicated in a variety of cancers. Recently wild-type p53 has been shown to exist in two interchangeable conformational variants, which ...
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Article
Liquid-crystal alignment of phthalocyanine-derived Langmuir-Blodgett films
Twisted nematic liquid crystals were uniformly aligned on Phthalocyanine (Pc)-derived Langmuir-Blodgett (LB) films. By scanning tunneling microscopy imaging, it was found that the Pc-LB film has a well-ordered...
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Article
Liquid-crystal alignment of rubbed polyimide films: A microscopic investigation
Rubbed polyimide films were investigated by Atomic Force Microscopy (AFM). On a large scale, microgrooves due to rubbing treatment were observed, whilst on a small scale, polyimide chain molecules were found t...
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Article
Bcl-xL is heterogeneously expressed by acute myeloblastic leukaemia cells and is associated with autonomous growth in vitro and with P-glycoprotein expression
The cells from approximately 70% patients with acute myeloblastic leukaemia exhibit autonomous growth characteristics in vitro, which have been associated with a poor response to therapy. We have previously shown...
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Article
Open AccessMechanisms of relapse in acute leukaemia: involvement of p53 mutated subclones in disease progression in acute lymphoblastic leukaemia
Mutations of the p53 tumour suppressor gene are infrequent at presentation of both acute myeloblastic leukaemia (AML) and acute lymphoblastic leukaemia (ALL), being found in between 5–10% of AML and 2–3% of ALL. ...
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Article
Molecular cytogenetic characterization and clinical relevance of additional, complex and/or variant chromosome abnormalities in acute promyelocytic leukemia
Acute promyelocytic leukemia (APL) is characterized by typical morphological manifestation, t(15;17) translocation and active response to all-trans retinoic acid (ATRA) in the great majority of patients. However,...
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Article
Production of Transgenic Soybean Plants with Two Anti-Fungal Protein Genes Via Agrobacterium and Particle Bombardment
Utilizing either Agrobacterium-mediated transformation or particle bombardment we obtained transgenic soybean [Glycine max (L.) Merr.] plants expressing the chitinase gene (chi) and the barley ribosome-inactivati...
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Article
Open AccessInterleukin-8/CXCL8 is a growth factor for human lung cancer cells
Interleukin-8/CXCL8 (IL-8) is a chemokine and angiogenic factor. Recently, IL-8 was identified as an autocrine growth factor in several human cancers. Here, we investigated the expression and function of IL-8 ...
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Article
Open AccessProduction and upregulation of granulocyte chemotactic protein-2/CXCL6 by IL-1β and hypoxia in small cell lung cancer
Small cell lung cancer (SCLC) is characterised by early and widespread metastasis. However, SCLC cells have so far been found to produce low levels of known pro-angiogenic factors. We speculated that SCLC cell...
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Article
Molecular response in acute promyelocytic leukemia: a direct comparison of regular and real-time RT-PCR
Evaluation of molecular response is important for the diagnosis and monitoring of minimal residual disease in patients with acute promyelocytic leukemia (APL). In this study, we analyzed the molecular response...
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Article
Protective effect of retinoid against endotoxin-induced mastitis in rats
A lipopolysaccharide (LPS) induced mastitis model in rats was used to study the protective effect of retinoid.
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Article
Interactive surgery simulation for the nose augmentation using CT data
Surgery to reshape the nose with an implant has been a regular procedure for enhancing a patient’s appearance and self-confidence. The purpose of this study was to establish a computed tomography (CT) based th...
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Article
ARF antagonizes the ability of Miz-1 to inhibit p53-mediated transactivation
Although Myc-interacting zinc-finger protein-1 (Miz-1) is known to be a poxvirus and zinc-finger (POZ) transcription factor required for Myc transcriptional repression, additional regulatory function of Miz-1 ...
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Article
3D Visualization and Simulation in Surgical Planning System of Orbital Hypertelorism
Simulation and three-dimensional visualization of object motion is a prerequisite for any surgical planning system. Orbital hypertelorism is a disease, which is most commonly associated with craniofacial malfo...
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Article
Successful Treatments of Two Human Avian Influenza Chinese Children and Follow-Up
Background and aims: Human H5N1 avian influenza caused worldwide attention in 1997 when the first case was found in Hong Kong, our present study is to summarize the clinical characteristics, diagnostic and therap...
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Article
Changes of Hypothalamus Corticotrophin Releasing Factor Levels in Ill Children with Acute Brain Injury
Background and aims: It has been proved that the secreting levels of corticotrophin releasing factor (CRF) were correlated with the TNF-α and IL-6 and hypoxia in animal experiments, our present study is to explor...
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Article
Effects Of CP-154,526 and Verapamil on Corticotrophin Releasing Factor Secreting Levels
Background and aims: We discovered that plasma corticotrophin releasing factor (CRF) levels in the young rats with hypoxic-ischemia (HI) brain damage were changeable, which was related with the time of HI. In pre...
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Article
Changes of Plasma Corticotrophin Releasing Factor Levels in the Young Rats with Hypoxic-Ischemic Brain Damage
Background and aims: It has been proved that the secreting levels of corticotrophin releasing factor (CRF) were correlated with the hypoxia in some animal experiments, our present study is to explore the changes ...
