5 Result(s)

Article

Mechanisms of relapse in acute leukaemia: involvement of p53 mutated subclones in disease progression in acute lymphoblastic leukaemia

Mutations of the p53 tumour suppressor gene are infrequent at presentation of both acute myeloblastic leukaemia (AML) and acute lymphoblastic leukaemia (ALL), being found in between 5–10% of AML and 2–3% of ALL. ...

Y-M Zhu, L Foroni, I G McQuaker, M Papaioannou, A Haynes… in British Journal of Cancer (1999)

Article

Interleukin-8/CXCL8 is a growth factor for human lung cancer cells

Interleukin-8/CXCL8 (IL-8) is a chemokine and angiogenic factor. Recently, IL-8 was identified as an autocrine growth factor in several human cancers. Here, we investigated the expression and function of IL-8 ...

Y M Zhu, S J Webster, D Flower, P J Woll in British Journal of Cancer (2004)

Article

Production and upregulation of granulocyte chemotactic protein-2/CXCL6 by IL-1β and hypoxia in small cell lung cancer

Small cell lung cancer (SCLC) is characterised by early and widespread metastasis. However, SCLC cells have so far been found to produce low levels of known pro-angiogenic factors. We speculated that SCLC cell...

Y M Zhu, S M Bagstaff, P J Woll in British Journal of Cancer (2006)

Article

Prognostic significance of monitoring leukemia-associated immunophenotypes by eight-color flow cytometry in adult B-acute lymphoblastic leukemia

Minimal residual disease (MRD) is of the most important factor for predicting prognosis and guiding treatment of acute lymphoblastic leukemia (ALL). In this study, we investigated the prognostic significance o...

X-Q Weng, Y Shen, Y Sheng, B Chen, J-H Wang, J-M Li, J-Q Mi… in Blood Cancer Journal (2013)

Article

Kinase-associated gene mutation pattern and clinical relevance in 205 patients with core binding factor leukemias

Y-S Chen, P-P Wang, Y Hu, Y-M Zhu, B Chen, J-Y Huang, J-M Li… in Blood Cancer Journal (2016)