Skip to main content

2 Result(s)

within Xuming Deng Remove this filter Chemistry Remove this filter English Remove this filter

and

  1. Article

    Open Access

    Repurposing harmaline as a novel approach to reverse tmexCD1-toprJ1-mediated tigecycline resistance against klebsiella pneumoniae infections

    A novel plasmid-mediated resistance–nodulation–division (RND) efflux pump gene cluster tmexCD1-toprJ1 in Klebsiella pneumoniae tremendously threatens the use of convenient therapeutic options in the post-antibiot...

    **dian Yang#, Lei Xu#, Yonglin Zhou, Minhe Cui, Dejun Liu… in Microbial Cell Factories (2024)

    Download PDF (8828 KB) View Article

  2. No Access

    Article

    Molecular modeling and QM/MM calculation clarify the catalytic mechanism of β-lactamase N1

    The treatment of bacterial infections is currently threatened by the emergence of pathogenic bacteria producing β-lactamase, which catalyzes the hydrolysis of β-lactams. Although the hydrolysis of the substrat...

    Yiding Yu, **yan Wang, Yawen Gao, Yanan Yang, Lin Sun… in Journal of Molecular Modeling (2019)