8 Result(s)

Article

Correction: Recruitment of LEF1 by Pontin chromatin modifier amplifies TGFBR2 transcription and activates TGFβ/SMAD signalling during gliomagenesis

Xuexia Zhou, Xuebing Li, Run Wang, Dan Hua, Cuiyun Sun, Lin Yu… in Cell Death & Disease (2024)

Article

Correction: Wilms’ tumour gene 1 (WT1) enhances non-small cell lung cancer malignancy and is inhibited by microRNA-498-5p

Xuebing Li, Wenzhe An, Hongli Pan, Yaguang Fan, Hua Huang, Yixuan Wang… in BMC Cancer (2023)

Article

Wilms’ tumour gene 1 (WT1) enhances non-small cell lung cancer malignancy and is inhibited by microRNA-498-5p

Wilms’ tumour gene 1 (WT1) is clearly recognized as a tumour promoter in diversiform of human malignancies. Nevertheless, knowledge of its expression, functions and potential molecular mechanisms in non-small ...

Xuebing Li, Wenzhe An, Hongli Pan, Yaguang Fan, Hua Huang, Yixuan Wang… in BMC Cancer (2023)

Article

Recruitment of LEF1 by Pontin chromatin modifier amplifies TGFBR2 transcription and activates TGFβ/SMAD signalling during gliomagenesis

Synergies of transcription factors, chromatin modifiers and their target genes are vital for cell fate determination in human cancer. Although the importance of numerous epigenetic machinery for regulating gli...

Xuexia Zhou, Xuebing Li, Run Wang, Dan Hua, Cuiyun Sun, Lin Yu… in Cell Death & Disease (2022)

Article

The ATPase Pontin is a key cell cycle regulator by amplifying E2F1 transcription response in glioma

Pontin (RUVBL1) is a highly conserved ATPase of the AAA + (ATPases Associated with various cellular Activities) superfamily and is implicated in various biological processes crucial for oncogenesis. Its overex...

Run Wang, Xuebing Li, Cuiyun Sun, Lin Yu, Dan Hua, Cuijuan Shi… in Cell Death & Disease (2021)

Article

miR-29s function as tumor suppressors in gliomas by targeting TRAF4 and predict patient prognosis

Robust proliferation and apoptosis inhibition of tumor cells are responsible for the high mortality and poor outcome of patients with high-grade gliomas. miR-29a/b/c have been reported to be important suppress...

Cuijuan Shi, Chun Rao, Cuiyun Sun, Lin Yu, Xuexia Zhou, Dan Hua… in Cell Death & Disease (2018)

Article

miR-29a/b/c function as invasion suppressors for gliomas by targeting CDC42 and predict the prognosis of patients

The lethality and poor outcome of high-grade gliomas result from the tumour relentless invasion. miR-29a/b/c downexpressions contribute to several human tumourigenesis. However, their relevance to prognosis an...

Cuijuan Shi, Linlin Ren, Cuiyun Sun, Lin Yu, **uwu Bian… in British Journal of Cancer (2017)