5 Result(s)
-
Article
Open AccessComparative study on the antituberculous effect and mechanism of the traditional Chinese medicines NiuBei**aoHe extract and JieHeWan
The traditional Chinese medicine NiuBei**aoHe (NBXH) extract and Chinese medicine preparation JieHeWan (JHW) exhibit anti-tuberculosis effects. The anti- tuberculosis effect of NBXH was compared with that of J...
-
Article
Open AccessSafety Evaluation of Recombinant Fusion Protein RP22 as a Skin Test Reagent for Tuberculosis Diagnosis: A Phase I Clinical Trial
This phase I clinical trial was conducted to evaluate the safety of RP22 as a skin test reagent for tuberculosis (TB) diagnosis and to explore the appropriate dosage.
-
Article
Open AccessEffects of Mycobacterium vaccae vaccine in a mouse model of tuberculosis: protective action and differentially expressed genes
Tuberculosis is a leading cause of death worldwide. BCG is an effective vaccine, but not widely used in many parts of the world due to a variety of issues. Mycobacterium vaccae (M. vaccae) is another vaccine used...
-
Article
Open AccessMannose-binding lectin 2 gene polymorphisms and their association with tuberculosis in a Chinese population
Immune- and inflammation-related genes (IIRGs) play an important role in the pathogenesis of tuberculosis (TB). However, the relationship between IIRG polymorphisms and TB risk remains unknown. In this study, ...
-
Article
Open AccessDiagnostic performance and problem analysis of commercial tuberculosis antibody detection kits in China
The diagnosis of bacterium-negative pulmonary tuberculosis (TB) and extra-pulmonary TB is challenging clinically. The detection of the anti-TB antibody has an important, auxiliary, clinical diagnostic value. T...
