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  1. Article

    Open Access

    Cell-specific NFIA upregulation promotes epileptogenesis by TRPV4-mediated astrocyte reactivity

    The astrocytes in the central nervous system (CNS) exhibit morphological and functional diversity in brain region-specific pattern. Functional alterations of reactive astrocytes are commonly present in human t...

    Shuo Kong, Tao-xiang Chen, **ang-lei Jia, Xue-lei Cheng… in Journal of Neuroinflammation (2023)

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  2. Article

    Inhibition of Transient Receptor Potential Vanilloid 4 (TRPV4) Mitigates Seizures

    Astrocytes are critical regulators of the immune/inflammatory response in several human central nervous system (CNS) diseases. Emerging evidence suggests that dysfunctional astrocytes are crucial players in se...

    Meng-liu Zeng, **g-**g Cheng, Shuo Kong, **ng-liang Yang… in Neurotherapeutics (2022)

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