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  1. Article

    Open Access

    Three-dimensional structure of Bax-mediated pores in membrane bilayers

    B-cell lymphoma 2 (Bcl-2)-associated X protein (Bax) is a member of the Bcl-2 protein family having a pivotal role in triggering cell commitment to apoptosis. Bax is latent and monomeric in the cytosol but tra...

    X-P Xu, D Zhai, E Kim, M Swift, J C Reed, N Volkmann, D Hanein in Cell Death & Disease (2013)

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  2. Article

    Open Access

    TRPM2 channel deficiency prevents delayed cytosolic Zn2+ accumulation and CA1 pyramidal neuronal death after transient global ischemia

    Transient ischemia is a leading cause of cognitive dysfunction. Postischemic ROS generation and an increase in the cytosolic Zn2+ level ([Zn2+]c) are critical in delayed CA1 pyramidal neuronal death, but the unde...

    M Ye, W Yang, J F Ainscough, X-P Hu, X Li, A Sedo, X-H Zhang… in Cell Death & Disease (2014)

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  3. Article

    Open Access

    MiR-216b is involved in pathogenesis and progression of hepatocellular carcinoma through HBx-miR-216b-IGF2BP2 signaling pathway

    This study aims to investigate the expression status of miRNA-216b in familial hepatocellular carcinoma (HCC) and the correlation between miRNA-216b expression and pathogenesis, as well as the progression of H...

    F-y Liu, S-j Zhou, Y-l Deng, Z-y Zhang, E-l Zhang, Z-b Wu… in Cell Death & Disease (2015)

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  4. Article

    Open Access

    Long intergenic non-coding RNA APOC1P1-3 inhibits apoptosis by decreasing α-tubulin acetylation in breast cancer

    Increasing evidence indicates that long non-coding RNAs (lncRNAs) act as important regulatory factors in tumor progression. However, their roles in breast cancer remain largely unknown. In present studies, we ...

    X-H Liao, J-G Wang, L-Y Li, D-M Zhou, K-H Ren, Y-T **, L Lv… in Cell Death & Disease (2016)

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