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  1. No Access

    Article

    Enhanced secretion of adhesive recognition sequence containing hirudin III mutein in E. coli

    It has been previously shown that Escherichia coli l-asparaginase II (l-ASP) signal peptide is capable of being utilized to direct extracellular secretion of hirudin III (HV3) in shake fla...

    Shuhua Tan, Wutong Wu, **angyu Li, Li Cui, Bing Li, Qi** Ruan in Molecular Biotechnology (2007)

  2. No Access

    Article

    Cytoglobin Exhibits Anti-Fibrosis Activity on Liver In Vivo and In Vitro

    Cytoglobin, generated using genetic engineering method, is a kind of recombinant human stellate cell activation-associated protein. We speculate that it could influence the development of hepatic fibrosis like...

    **n He, Ruoyun Lv, Ke Wang, **aofeng Huang, Wutong Wu, Lifang Yin… in The Protein Journal (2011)

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    Article

    Construction, Expression and Refolding of a Bifunctional Fusion Protein Consisting of C-Terminal 12-Residue of Hirudin-PA and Reteplase

    To obtain a bifunctional protein simultaneously showing bioactivity of anticoagulant and fibrinolytic for use in the treatment of thrombotic diseases, we constructed a fusion protein (HV12p–rPA) containing C-t...

    Ling Gao, Chun Zhang, Lingling Li, Lan Liang, Xuan Deng, Wutong Wu… in The Protein Journal (2012)