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  1. Article

    Open Access

    The proteasome modulates endocytosis specifically in glomerular cells to promote kidney filtration

    Kidney filtration is ensured by the interaction of podocytes, endothelial and mesangial cells. Immunoglobulin accumulation at the filtration barrier is pathognomonic for glomerular injury. The mechanisms that ...

    Wiebke Sachs, Lukas Blume, Desiree Loreth, Lisa Schebsdat in Nature Communications (2024)

  2. Article

    Open Access

    Publisher Correction: Non-functional ubiquitin C-terminal hydrolase L1 drives podocyte injury through impairing proteasomes in autoimmune glomerulonephritis

    Julia Reichelt, Wiebke Sachs, Sarah Frömbling, Julia Fehlert in Nature Communications (2023)

  3. Article

    Open Access

    Non-functional ubiquitin C-terminal hydrolase L1 drives podocyte injury through impairing proteasomes in autoimmune glomerulonephritis

    Little is known about the mechanistic significance of the ubiquitin proteasome system (UPS) in a kidney autoimmune environment. In membranous nephropathy (MN), autoantibodies target podocytes of the glomerular...

    Julia Reichelt, Wiebke Sachs, Sarah Frömbling, Julia Fehlert in Nature Communications (2023)