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  1. Article

    Open Access

    Visualization of tumor heterogeneity and prediction of isocitrate dehydrogenase mutation status for human gliomas using multiparametric physiologic and metabolic MRI

    This study aimed to differentiate isocitrate dehydrogenase (IDH) mutation status with the voxel-wise clustering method of multiparametric magnetic resonance imaging (MRI) and to discover biological underpinnin...

    Akifumi Hagiwara, Hiroyuki Tatekawa, **gwen Yao, Catalina Raymond in Scientific Reports (2022)

  2. Article

    Open Access

    Decorin expression is associated with predictive diffusion MR phenotypes of anti-VEGF efficacy in glioblastoma

    Previous data suggest that apparent diffusion coefficient (ADC) imaging phenotypes predict survival response to anti-VEGF monotherapy in glioblastoma. However, the mechanism by which imaging may predict clinic...

    Kunal S. Patel, **gwen Yao, Catalina Raymond, William Yong in Scientific Reports (2020)

  3. Article

    Open Access

    Human IDH mutant 1p/19q co-deleted gliomas have low tumor acidity as evidenced by molecular MRI and PET: a retrospective study

    Co-deletion of 1p/19q is a hallmark of oligodendroglioma and predicts better survival. However, little is understood about its metabolic characteristics. In this study, we aimed to explore the extracellular ac...

    **gwen Yao, Akifumi Hagiwara, Catalina Raymond, Soroush Shabani in Scientific Reports (2020)

  4. Article

    Open Access

    Validation of vessel size imaging (VSI) in high-grade human gliomas using magnetic resonance imaging, image-guided biopsies, and quantitative immunohistochemistry

    To evaluate the association between a vessel size index (VSIMRI) derived from dynamic susceptibility contrast (DSC) perfusion imaging using a custom spin-and-gradient echo echoplanar imaging (SAGE-EPI) sequence a...

    Ararat Chakhoyan, **gwen Yao, Kevin Leu, Whitney B. Pope in Scientific Reports (2019)