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Pharmacogenomics

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  1. Article

    Human pharmacogenomics: The development of a science

    Until about 50 years ago, the altering of a normal drug effect by a genetic deficiency was only rarely observed. Here, my discovery of the genetic variant of butyrylcholinesterase affecting succinylcholine act...

    Werner Kalow in Human Genomics (2004)

  2. Article

    Atypical plasma cholinesterase. A personal discovery story: a tale of three cities

    Werner Kalow in Canadian Journal of Anesthesia (2004)

  3. Article

    Comparison of effects of several inhalation anaesthetics on caffeine-induced contractures of normal and malignant hyperthermic skeletal muscle

    We have compared the combined effects of halothane, enflurane, isoflurane and methoxyflurane on caffeine-induced contractures of normal and malignant hyperthermia susceptible (MHS) skeletal muscle fascicles. W...

    Beverley A. Britt, Laszlo Endrenyi, Wanda Frodis in Canadian Anaesthetists’ Society Journal (1980)

  4. Article

    The adenosine triphosphate (ATP) depletion test: Comparison with the caffeine contracture test as a method of diagnosing malignant hyperthermia susceptibility

    The adenosine triphosphate (ATP depletion ratio, which is the ratio [ATP] in skeletal muscle equilibrated with carbogen and 4% halothane for 30 minutes/

    Beverley A. Britt, Laszlo Endrenyi, Werner Kalow in Canadian Anaesthetists’ Society Journal (1976)

  5. Article

    Errata

    Beverly A. Britt, Werner Kalow, Alan Gordon in Canadian Anaesthetists’ Society Journal (1974)

  6. Article

    Malignant hyperthermia: an investigation of five patients

    Beverley A. Britt, Werner Kalow, Alan Gordon in Canadian Anaesthetists’ Society Journal (1973)

  7. Article

    A clinical and laboratory evaluation of four fluothane vaporizers

    A la suite de ľintérêt qu’on a porté, récemment, au Fluothane, on a dû fabriquer plusieurs vaporisateurs pour administrer cet agent anesthésique puissant. Cet article fait part des résultats des recherches de ...

    Iain M MacKay, Werner Kalow in Canadian Anaesthetists’ Society Journal (1958)

  8. Article

    Spectrophotometric determination of fluothane vapour

    The optical properties of Fluothane vapour have been determined. There was a strong absorption of ultraviolet and infrared radiation. While the absorption in either range can be used to measure the concentrati...

    Werner Kalow in Canadian Anaesthetists’ Society Journal (1957)

  9. Article

    The relation of plasma cholinesterases to response to clinical doses of succinylcholine

    The plasma cholinesterase of a normal adult is capable of destroyingin vitro up to 120 mg. per minute of succinylcholme chloride. This great speed of destruction cannot be obtainedin vivo, yet the normal plasma c...

    Werner Kalow in Canadian Anaesthetists’ Society Journal (1956)

  10. Article

    Experiments with animals on the combined action of procaine and barbiturates

    Procaine prolonged the sleep of guinea-pigs induced by pentobarbital.

    Madelaine O Maykut, Werner Kalow in Canadian Anaesthetists’ Society Journal (1955)