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  1. Article

    Open Access

    Establishment of the prognostic index of lung squamous cell carcinoma based on immunogenomic landscape analysis

    The incidence of lung squamous cell carcinoma (LUSC) increased substantially in recent years. Systematical investigation of the immunogenomic pattern is critical to improve the prognosis of LUSC.

    Jianguo Zhang, Jianzhong Zhang, Cheng Yuan, Yuan Luo… in Cancer Cell International (2020)

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    Article

    Non-canonical NF-κB signalling and ETS1/2 cooperatively drive C250T mutant TERT promoter activation

    Transcriptional reactivation of TERT, the catalytic subunit of telomerase, is necessary for cancer progression in about 90% of human cancers. The recent discovery of two prevalent somatic mutations—C250T and C...

    Yinghui Li, Qi-Ling Zhou, Wenjie Sun, Prashant Chandrasekharan… in Nature Cell Biology (2015)