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    Non-canonical NF-κB signalling and ETS1/2 cooperatively drive C250T mutant TERT promoter activation

    Transcriptional reactivation of TERT, the catalytic subunit of telomerase, is necessary for cancer progression in about 90% of human cancers. The recent discovery of two prevalent somatic mutations—C250T and C...

    Yinghui Li, Qi-Ling Zhou, Wenjie Sun, Prashant Chandrasekharan in Nature Cell Biology (2015)