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  1. Article

    Open Access

    Strain level microbial detection and quantification with applications to single cell metagenomics

    Computational identification and quantification of distinct microbes from high throughput sequencing data is crucial for our understanding of human health. Existing methods either use accurate but computationa...

    Kaiyuan Zhu, Alejandro A. Schäffer, Welles Robinson, Junyan Xu in Nature Communications (2022)

  2. Article

    Open Access

    Harnessing synthetic lethality to predict the response to cancer treatment

    While synthetic lethality (SL) holds promise in develo** effective cancer therapies, SL candidates found via experimental screens often have limited translational value. Here we present a data-driven approac...

    Joo Sang Lee, Avinash Das, Livnat Jerby-Arnon, Rand Arafeh in Nature Communications (2018)

  3. Article

    Open Access

    Putative functional genes in idiopathic dilated cardiomyopathy

    Idiopathic dilated cardiomyopathy (DCM) is a complex disorder with a genetic and an environmental component involving multiple genes, many of which are yet to be discovered. We integrate genetic, epigenetic, t...

    Nishanth Ulhas Nair, Avinash Das, Uri Amit, Welles Robinson in Scientific Reports (2018)