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    Chapter

    Genetic Regulatory Networks Guiding Islet Development

    The pancreatic islet is a mini-organ that consists of several hormone-secreting endocrine cell types in adults. Islets execute a vital physiological function in regulating glucose homeostasis, and endocrine ce...

    **n-**n Yu, **n Wang, Wei-Lin Qiu, Liu Yang in Pluripotent Stem Cell Therapy for Diabetes (2023)

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    Article

    Sequential progenitor states mark the generation of pancreatic endocrine lineages in mice and humans

    The pancreatic islet contains multiple hormone+ endocrine lineages (α, β, δ, PP and ε cells), but the developmental processes that underlie endocrinogenesis are poorly understood. Here, we generated novel mouse l...

    **n-**n Yu, Wei-Lin Qiu, Liu Yang, Yan-Chun Wang, Mao-Yang He, Dan Wang in Cell Research (2021)

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    Article

    Single-cell patterning and axis characterization in the murine and human definitive endoderm

    Defining the precise regionalization of specified definitive endoderm progenitors is critical for understanding the mechanisms underlying the generation and regeneration of respiratory and digestive organs, ye...

    Lin-Chen Li, **n Wang, Zi-Ran Xu, Yan-Chun Wang, Ye Feng, Liu Yang in Cell Research (2021)