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Open AccessCysteinyl Leukotriene Receptor Antagonists Decrease Cancer Risk in Asthma Patients
Previous in vitro and in vivo studies have demonstrated the potential of using cysteinyl leukotriene receptor antagonists (LTRAs) for chemoprevention, but this has not been investigated in any clinical setting. W...
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Open AccessCorrection: Corrigendum: Cysteinyl Leukotriene Receptor Antagonists Decrease Cancer Risk in Asthma Patients
Scientific Reports 6: Article number: 23979; Published online: 07 April 2016; Updated: 12 May 2016 The Acknowledgements section in this Article is incomplete: “The authors thank the help from the Statistical A...
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Open AccessCXCL17-derived CD11b+Gr-1+ myeloid-derived suppressor cells contribute to lung metastasis of breast cancer through platelet-derived growth factor-BB
Metastasis is the major cause of death from breast cancer. Colonization and adaption of metastatic cells in distant organs is a rate-limiting step of the cancer spreading. The underlying mechanisms responsible...
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Bone-marrow-derived cell-released extracellular vesicle miR-92a regulates hepatic pre-metastatic niche in lung cancer
Metastatic tumors have been shown to establish a supportive pre-metastatic niche (PMN) in distant organs, which in turn determines disseminated tumor cells’ targeting of such organs. PMN is formed through the ...
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Open AccessImpact of corticosteroid treatment on clinical outcomes of influenza-associated ARDS: a nationwide multicenter study
Corticosteroid treatment has been widely used in the treatment of septic shock, influenza, and ARDS, although some previous studies discourage its use in severe influenza patients. This multicenter retrospecti...
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Open AccessProximal tubule-derived exosomes contribute to mesangial cell injury in diabetic nephropathy via miR-92a-1-5p transfer
Diabetic nephropathy (DN) is an increasing threat to human health and regarded to be the leading cause of end-stage renal disease worldwide. Exosomes delivery may play a key role in cross-talk among kidney cel...
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Open AccessSingle-cell transcriptomic profiles in the pathophysiology within the microenvironment of early diabetic kidney disease
Diabetic kidney disease (DKD) is the leading cause of end-stage kidney disease, resulting in a huge socio-economic impact. Kidney is a highly complex organ and the pathogenesis underlying kidney organization i...
