465 Result(s)
within
Wei-**ng Bao
English
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Article
Open AccessPhase separation of RNF214 promotes the progression of hepatocellular carcinoma
Hepatocellular carcinoma (HCC) is one of the most common malignant tumors, and the expression and function of an uncharacterized protein RNF214 in HCC are still unknown. Phase separation has recently been obse...
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Theoretical Exploration of Alloying Effects on Stabilities and Mechanical Properties of γʹ Phase in Novel Co–Al–Nb-Base Superalloys
The new developed γ/γʹ Co–Al–Nb-base alloys show great potentials as high-temperature materials. However, finding appropriate compositions to improve performance of alloys still poses a great challenge to the dev...
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Design and fabrication of lightweight AlCrFeNiTix compositionally complex alloys with exceptional specific strength
This study focuses on compositionally complex alloys (CCAs), aiming to achieve a balance between high strength and low density for new energy and aerospace applications. The composition of AlCrFeNiTix CCAs is str...
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Open AccessCorrection: PAX6 promotes neuroendocrine phenotypes of prostate cancer via enhancing MET/STAT5Amediated chromatin accessibility
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Characteristics of tandem repeat inheritance and sympathetic nerve involvement in GAA-FGF14 ataxia
Intronic GAA repeat expansion ([GAA] ≥250) in FGF14 is associated with the late-onset neurodegenerative disorder, spinocerebellar ataxia 27B (SCA27B, GAA-FGF14 ataxia). We aim to determine the prevalence of the G...
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Open AccessIdebenone Antagonizes P53-Mediated Neuronal Oxidative Stress Injury by Regulating CD38-SIRT3 Protein Level
Idebenone, an antioxidant used in treating oxidative damage-related diseases, has unclear neuroprotective mechanisms. Oxidative stress affects cell and mitochondrial membranes, altering Adp-ribosyl cyclase (CD...
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Open AccessDe novo design of a nanoregulator for the dynamic restoration of ovarian tissue in cryopreservation and transplantation
The cryopreservation and transplantation of ovarian tissue underscore its paramount importance in safeguarding reproductive capacity and ameliorating reproductive disorders. However, challenges persist in ovar...
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Zeb1-controlled metabolic plasticity enables remodeling of chromatin accessibility in the development of neuroendocrine prostate cancer
Cell plasticity has been found to play a critical role in tumor progression and therapy resistance. However, our understanding of the characteristics and markers of plastic cellular states during cancer cell l...
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Stepped-up development of accelerator mass spectrometry method for the detection of 60Fe with the HI-13 tandem accelerator
The Moon provides a unique environment for investigating nearby astrophysical events such as supernovae. Lunar samples retain valuable information from these events, via detectable long-lived “fingerprint” rad...
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Chemical constituents from the aerial parts of Rhododendron thymifolium and its bioactivities against Tribolium castaneum, Lasioderma serricorne, and Ditylenchus destructor
This study investigated chemical compositions and biocidal activities from the aerial parts of Rhododendron thymifolium against Tribolium castaneum, Lasioderma serricorne, and Ditylenchus destructor. In total, 13...
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Open AccessPAX6 promotes neuroendocrine phenotypes of prostate cancer via enhancing MET/STAT5A-mediated chromatin accessibility
Neuroendocrine prostate cancer (NEPC) is a lethal subset of prostate cancer which is characterized by neuroendocrine differentiation and loss of androgen receptor (AR) signaling. Growing evidence reveals that ...
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“Kill the familiar effect”: the impact of anger on deceptive behavior
Emotions can change individuals’ perceptions of social distance and, consequently, their deceptive behavior. Anger is a highly destructive emotion; however, its effects on social distance and deception are unc...
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Characteristics of multi-channel reservoir computing based on mutually-coupled spin-VCSELs: a comprehensive investigation
We studied the characteristics of a four-channel multi-task reservoir computing (RC) system based on mutually-coupled and optically pumped spin vertical-cavity surface-emitting lasers (Spin-VCSELs). By analyzi...
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Open AccessA chromosomal-scale genome assembly of modern cultivated hybrid sugarcane provides insights into origination and evolution
Sugarcane is a vital crop with significant economic and industrial value. However, the cultivated sugarcane’s ultra-complex genome still needs to be resolved due to its high ploidy and extensive recombination ...
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Open AccessXELOX (capecitabine plus oxaliplatin) plus bevacizumab (anti-VEGF-A antibody) with or without adoptive cell immunotherapy in the treatment of patients with previously untreated metastatic colorectal cancer: a multicenter, open-label, randomized, controlled, phase 3 trial
Fluoropyrimidine-based combination chemotherapy plus targeted therapy is the standard initial treatment for unresectable metastatic colorectal cancer (mCRC), but the prognosis remains poor. This phase 3 trial ...
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Features and formulae of sediment incipient motion in vegetated flow environment
Aquatic vegetation is a vital component of natural river ecosystems, playing a crucial role in maintaining ecological balance, providing habitat and improving water quality. However, the presence of vegetation...
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Attosecond-resolved non-dipole photoionization dynamics
Light–matter interactions are usually described within the electric-dipole approximation, where the magnetic-field component and the spatial variation of the light electric field over the relevant electronic l...
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Open AccessInduction immunotherapy plus chemotherapy followed by definitive chemoradiation therapy in locally advanced esophageal squamous cell carcinoma: a propensity-score matched study
For patients with unresectable locally advanced esophageal squamous cell carcinoma (ESCC), concurrent chemoradiotherapy (CCRT) is the current standard treatment; however, the prognosis remains poor. Immunother...
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Open AccessRuxolitinib induces apoptosis and pyroptosis of anaplastic thyroid cancer via the transcriptional inhibition of DRP1-mediated mitochondrial fission
Anaplastic thyroid carcinoma (ATC) has a 100% disease-specific mortality rate. The JAK1/2-STAT3 pathway presents a promising target for treating hematologic and solid tumors. However, it is unknown whether the...
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Nondestructive technique for identifying nuclides using neutron resonance transmission analysis at CSNS Back-n
Nondestructive and noninvasive neutron assays are essential applications of neutron techniques. Neutron resonance transmission analysis (NRTA) is a powerful nondestructive method for investigating the elementa...
