39 Result(s)
within
Wei Fan
Science, Humanities and Social Sciences, multidisciplinary
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Article
Role of melanocortinergic neurons in feeding and the agouti obesity syndrome
DOMINANT alleles at the agouti locus (A) cause an obesity syndrome in the mouse, as a consequence of ectopic expression of the agouti peptide1–6. This peptide, normally only found in the skin, is a high-affinity ...
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Article
Experimental investigation of effect of partial filling on the impulse of pulse detonation engine
Using poor-detonable liquid C8H16/air mixture with low-energy system (total spark energy of 50 mJ) and a new one-step detonation initiation method developed in this study, partial-tube fill experiments have been ...
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Article
Open AccessThe diploid genome sequence of an Asian individual
Here we present the first diploid genome sequence of an Asian individual. The genome was sequenced to 36-fold average coverage using massively parallel sequencing technology. We aligned the short reads onto th...
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Article
Neuropeptide Y and gamma-melanocyte stimulating hormone (γ-MSH) share a common pressor mechanism of action
Central circuits known to regulate food intake and energy expenditure also affect central cardiovascular regulation. For example, both the melanocortin and neuropeptide Y (NPY) peptide families, known to regul...
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Article
Open AccessThe sequence and de novo assembly of the giant panda genome
Using next-generation sequencing technology alone, we have successfully generated and assembled a draft sequence of the giant panda genome. The assembled contigs (2.25 gigabases (Gb)) cover approximately 94% o...
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Erratum: The sequence and de novo assembly of the giant panda genome
Nature 463, 311–317 (2010) In this Article, the Latin species name of the giant panda was written incorrectly as Ailuropoda melanoleura. The correct name is Ailuropoda melanoleuca.
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Article
Open AccessPromoting Interspecies Electron Transfer with Biochar
Biochar, a charcoal-like product of the incomplete combustion of organic materials, is an increasingly popular soil amendment designed to improve soil fertility. We investigated the possibility that biochar co...
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Open AccessReactive Liftoff of Crystalline Cellulose Particles
The condition of heat transfer to lignocellulosic biomass particles during thermal processing at high temperature (>400 °C) dramatically alters the yield and quality of renewable energy and fuels. In this work...
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Article
Open AccessMicro-CT evaluation of apical delta morphologies in human teeth
The apical delta is an intricate system within the root canal and incompletely debridement may affect the long-term prognosis of root canal therapy. The aim of the present study is to investigate the morpholog...
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Article
Open AccessThe ERF transcription factor family in cassava: genome-wide characterization and expression analyses against drought stress
Cassava (Manihot esculenta) shows strong tolerance to drought stress; however, the mechanisms underlying this tolerance are poorly understood. Ethylene response factor (ERF) family genes play a crucial role in pl...
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Article
Open AccessExpression and distribution of extensins and AGPs in susceptible and resistant banana cultivars in response to wounding and Fusarium oxysporum
Banana Fusarium wilt caused by Fusarium oxysporum f. sp. cubense (Foc) is soil-borne disease of banana (Musa spp.) causing significant economic losses. Extensins and arabinogalactan proteins (AGPs) are cell wall ...
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Article
Ultra-selective high-flux membranes from directly synthesized zeolite nanosheets
A direct synthesis of high-aspect-ratio microporous zeolite nanosheets and the use of such nanosheets in separation membranes are described.
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Article
Open AccessReactive Hyperemia Index in Patients on Maintenance Hemodialysis: Cross-sectional Data from a Cohort Study
Previous studies suggested that the reactive hyperemia index (RHI) is a promising cardiovascular risk predictor. We aimed to evaluate clinical determinants of RHI and its association with circulating endotheli...
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Article
Open AccessConsciously over Unconsciously Perceived Rewards Facilitate Self-face Processing: An ERP Study
Consciously and unconsciously perceived rewards are thought to modulate essential cognitive processes in different ways. However, little is known about whether and how they modulate higher-order social cogniti...
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Article
Open AccessIdentification of candidate genes involved in isoquinoline alkaloids biosynthesis in Dactylicapnos scandens by transcriptome analysis
Dactylicapnos scandens (D. Don) Hutch (Papaveraceae) is a well-known traditional Chinese herb used for treatment of hypertension, inflammation, bleeding and pain for centuries. Although t...
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Article
Open AccessRenal iron accumulation occurs in lupus nephritis and iron chelation delays the onset of albuminuria
Proteins involved in iron homeostasis have been identified as biomarkers for lupus nephritis, a serious complication of systemic lupus erythematosus (SLE). We tested the hypothesis that renal iron accumulation...
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Article
Open AccessThe Relationship between Secondary Forest and Environmental Factors in the Southern Taihang Mountains
It is important to understand the effects of environmental factors on secondary forest assembly for effective afforestation and vegetation restoration. We studied 24 20 m × 20 m quadrats of natural secondary f...
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Article
Open AccessEngineering yeast for the production of breviscapine by genomic analysis and synthetic biology approaches
The flavonoid extract from Erigeron breviscapus, breviscapine, has increasingly been used to treat cardio- and cerebrovascular diseases in China for more than 30 years, and plant supply of E. breviscapus is becom...
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Article
Open AccessComparative Study of Subcutaneous and Orthotopic Mouse Models of Prostate Cancer: Vascular Perfusion, Vasculature Density, Hypoxic Burden and BB2r-Targeting Efficacy
The gastrin-releasing peptide receptor (BB2r) is overexpressed in a variety of cancers including prostate cancer. As a consequence, the development of BB2r-targeted diagnostic/therapeutic radiopharmaceuticals ...
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Article
Open AccessSequencing of Chinese castor lines reveals genetic signatures of selection and yield-associated loci
Oil produced by castor (Ricinus communis) has broad industrial applications. However, knowledge on the genetic diversity, especially genetic alterations that occurred during domestication and subsequent traits se...
