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Article
Open AccessAggregation promotes charge separation in fullerene-indacenodithiophene dyad
Fast photoinduced charge separation (CS) and long-lived charge-separated state (CSS) in small-molecules facilitate light-energy conversion, while simultaneous attainment of both remains challenging. Here we ac...
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Article
Open AccessAnalysis of the synergistic benefits of typical technologies for pollution reduction and carbon reduction in the iron and steel industry in the Bei**g–Tian**–Hebei region
With its high energy consumption and pollutant emissions, the iron and steel industry is a significant source of air pollution and carbon emissions in the Bei**g–Tian**–Hebei (BTH) region. To improve air qua...
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Article
Open AccessUncovering the characteristics of the gut microbiota in patients with ischemic stroke and hemorrhagic stroke
This study aimed to explore the gut microbiota characteristics of ischemic and hemorrhagic stroke patients. A case–control study was conducted, and high-throughput sequencing of the V4–V5 region of 16S rRNA wa...
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Article
Open AccessIncreased prevalence but decreased survival of nonviral hepatocellular carcinoma compared to viral hepatocellular carcinoma in recent ten years
Due to the comprehensive hepatitis B virus vaccination program in Taiwan since 1986, the development of antiviral therapy for chronic hepatitis B and chronic hepatitis C infection and covered by National healt...
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Article
Open AccessThe EIF3H-HAX1 axis increases RAF-MEK-ERK signaling activity to promote colorectal cancer progression
Eukaryotic initiation translation factor 3 subunit h (EIF3H) plays critical roles in regulating translational initiation and predicts poor cancer prognosis, but the mechanism underlying EIF3H tumorigenesis rem...
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Article
Open AccessBiomimetic nanocluster photoreceptors for adaptative circular polarization vision
Nanoclusters with atomically precise structures and discrete energy levels are considered as nanoscale semiconductors for artificial intelligence. However, nanocluster electronic engineering and optoelectronic...
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Article
Open AccessFlow study of Dean’s instability in high aspect ratio microchannels
Dean’s flow and Dean’s instability have always been important concepts in the inertial microfluidics. Curved channels are widely used for applications like mixing and sorting but are limited to Dean’s flow onl...
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Article
Open AccessConstruction and integrated analysis of the ceRNA network hsa_circ_0000672/miR-516a-5p/TRAF6 and its potential function in atrial fibrillation
Atrial fibrosis is a crucial contributor to initiation and perpetuation of atrial fibrillation (AF). This study aimed to identify a circRNA-miRNA-mRNA competitive endogenous RNA (ceRNA) regulatory network rela...
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Article
Open AccessEffects of Mn content on austenite stability and mechanical properties of low Ni alumina-forming austenitic heat-resistant steel: a first-principles study
Low Ni alumina-forming austenitic (AFA) heat-resistant steel is an advanced high-temperature stainless steel with reduced cost, good machinability, high-temperature creep strength, and high-temperature corrosi...
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Article
Open AccessRole of cardiac mitofusins in cardiac conduction following simulated ischemia–reperfusion
Mitochondrial dysfunction induced by acute cardiac ischemia–reperfusion (IR), may increase susceptibility to arrhythmias by perturbing energetics, oxidative stress production and calcium homeostasis. Although ...
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Article
Open AccessTargeting endogenous kidney regeneration using anti-IL11 therapy in acute and chronic models of kidney disease
The kidney has large regenerative capacity, but this is compromised when kidney damage is excessive and renal tubular epithelial cells (TECs) undergo SNAI1-driven growth arrest. Here we investigate the role of...
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Article
Open AccessChiral aldehyde-nickel dual catalysis enables asymmetric α−propargylation of amino acids and stereodivergent synthesis of NP25302
The combined catalytic systems derived from organocatalysts and transition metals exhibit powerful activation and stereoselective-control abilities in asymmetric catalysis. This work describes a highly efficie...
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Article
Open AccessGlaucoma diagnostic performance of macular ganglion cell complex thickness using regular and long axial length normative databases
The risks of misdiagnosing a healthy individual as glaucomatous or vice versa may be high in a population with a large majority of highly myopic individuals, due to considerable morphologic variability in high...
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Article
Open AccessEvidence of water on the lunar surface from Chang’E-5 in-situ spectra and returned samples
The distribution range, time-varying characteristics, and sources of lunar water are still controversial. Here we show the Chang’E-5 in-situ spectral observations of lunar water under Earth’s magnetosphere shi...
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Article
Open AccessA digital SIW-slot antenna array with FPGA implementation of beamforming
The future satellite platform and 5G communication systems place high demands on antennas, in which the antenna should offer low-cost, lightweight, electronically steerable features. In this paper, the design ...
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Article
Open AccessCatalytic asymmetric Tsuji–Trost α−benzylation reaction of N-unprotected amino acids and benzyl alcohol derivatives
Catalytic asymmetric Tsuji–Trost benzylation is a promising strategy for the preparation of chiral benzylic compounds. However, only a few such transformations with both good yields and enantioselectivities ha...
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Article
Open AccessA weakly supervised deep learning-based method for glioma subtype classification using WSI and mpMRIs
Accurate glioma subtype classification is critical for the treatment management of patients with brain tumors. Develo** an automatically computer-aided algorithm for glioma subtype classification is challeng...
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Article
Open AccessPrognostic value and underlying mechanism of autophagy-related genes in bladder cancer
Bladder cancer (BLCA) is the most common malignancy whose early diagnosis can ensure a better prognosis. However, the predictive accuracy of commonly used predictors, including patients’ general condition, his...
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Article
Open AccessNationwide registry of glecaprevir plus pibrentasvir in the treatment of HCV in Taiwan
The study evaluated the real-world treatment outcomes of Glecaprevir/pibrentasvir (GLE/PIB) including effectiveness, safety and healthcare resource utilization based on a nation-wide registry in Taiwan. The Ta...
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Article
Open AccessMagnetoactive acoustic metamaterials based on nanoparticle-enhanced diaphragm
Magnetoactive membrane-type acoustic metamaterials are fabricated by coating a layer of magnetic nanoparticles on the polyethylene (PE) membranes and their vibration characters are investigated experimentally....